Variations in Essential Oil Compositions of <i>Lavandula pubescens</i> (Lamiaceae) Aerial Parts Growing Wild in Yemen

Al-Badani, Rowaida N.; Silva, Joyce Kelly R. da; Setzer, William N.; Ali, Nasser A. Awadh; Muharam, Bushra A.; Alfahad, Ahmed J.

doi:10.1002/cbdv.201600286

Cited by 12 publications

(12 citation statements)

References 19 publications

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“…Sesquiterpene hydrocarbons accounted for 13.1%, with β-bisabolene as the most abundant (9.1%). The predominance of carvacrol and methyl carvacrol as the most abundant compounds in the L. pubescens EO of this study is in accordance with published compositions of the EOs hydrodistilled from several Yemeni specimens [ 29 , 30 ]. This species is, indeed, reported as having a phenolic-type EO profile among species belonging to this genus [ 39 ].…”

Section: Resultssupporting

confidence: 91%

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Essential Oil Analysis and Antimicrobial Evaluation of Three Aromatic Plant Species Growing in Saudi Arabia

et al. 2021

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Arabian flora is a rich source of bioactive compounds. In this study, we investigated three aromatic plant species with the aim of finding valuable sources of antimicrobial agents against common pathogenic microorganisms. We focused especially on microorganisms, which cause outbreaks of infectious disease during mass gatherings and pilgrimages season in Saudi Arabia. The essential oils of three aromatic plant species were hydrodistilled from flowering aerial parts of Lavandula pubescens Decne. and Pulicaria incisa subsp. candolleana E.Gamal-Eldin, and from leaves, stems, ripe and unripe fruits of Juniperus procera Hochst. Ex Endl. They were subsequently analyzed by gas chromatography-mass spectrometry (GC-MS). The main constituents of L. pubescens were found to be carvacrol (55.7%), methyl carvacrol (13.4%), and β-bisabolene (9.1%). P. incisa subsp. Candolleana essential oil was rich in linalool (33.0%), chrysanthenone (10.3%), eugenol (8.9%), and cis-chrysanthenol (8.0%); the major components of J. procera essential oil were α-pinene (31.3–62.5%) and δ-3-carene (7.3–30.3%). These essential oils were tested against thirteen American Type Culture Collection (ATCC) strains of Gram-positive and Gram-negative bacteria using the agar diffusion assay. The only effective essential oil was that of L. pubescens and the most sensitive strains were Acinetobacter baumannii, Salmonella typhimurium, Shigella sonnei, Enterococcus faecalis and Staphylococcus epidermidis. Carvacrol, the major constituent of L. pubescens, was tested on these strains and was compared with vancomycin, amikacin, and ciprofloxacin. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) assays of L. pubescens essential oil and carvacrol revealed that Gram-negative strains were more susceptible than the Gram-positive ones.

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Section: Resultssupporting

confidence: 91%

“…L. pubescens is reported in the literature as a species commonly found among the wild flora in Middle-Eastern Asia and Mediterranean Africa; it is, indeed, mainly reported as growing in Palestine [ 28 ], Yemen [ 29 , 30 , 31 ], Saudi Arabia [ 32 , 33 , 34 ]. For P. incisa subsp.…”

Section: Introductionmentioning

confidence: 99%

Essential Oil Analysis and Antimicrobial Evaluation of Three Aromatic Plant Species Growing in Saudi Arabia

et al. 2021

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“…e oxygenated monoterpenes were the dominant (73.26%) chemical group within the constituents, followed by sesquiterpene hydrocarbons (13.84%), monoterpene hydrocarbons (11.79%), and oxygenated sesquiterpenes (1.11%). e EO chemical profile in this study is qualitatively comparable to that formerly reported from Yemen where the EO has shown to be carvacrol chemotype (60.9-77.5%) [6,31].…”

Section: Gc-ms Analysissupporting

confidence: 87%

“…ere are no reports on the EO composition of L. pubescens growing wild in Palestine and only a few such reports are available worldwide [6,8,13,31]. Hydrodistillation of the L. pubescens leaves yielded 1.9 mL per 250 g fresh plant material.…”

Section: Gc-ms Analysismentioning

confidence: 99%

Downy Lavender Oil: A Promising Source of Antimicrobial, Antiobesity, and Anti‐Alzheimer’s Disease Agents

Ali‐Shtayeh¹,

Abu-Zaitoun²,

Dudai

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Lavandula pubescens Decne (LP) is one of the three Lavandula species growing wildly in the Dead Sea Valley, Palestine. The products derived from the plant, including the essential oil (EO), have been used in Traditional Arabic Palestinian Herbal Medicine (TAPHM) for centuries as therapeutic agents. The EO is traditionally believed to have sedative, anti-inflammatory, antiseptic, antidepressive, antiamnesia, and antiobesity properties. This study was therefore aimed to assess the in vitro bioactivities associated with the LP EO. The EO was separated by hydrodistillation from the aerial parts of LP plants and analyzed for its antioxidant, antimicrobial, anticholinesterase, and antilipase activities. GC-MS was used for phytochemical analysis. The chemical analysis of the EO composition revealed 25 constituents, of which carvacrol (65.27%) was the most abundant. EO exhibited strong antioxidant (IC50 0.16–0.18 μL/mL), antiacetylcholinesterase (IC50 0.9 μL/mL), antibutyrylcholinesterase (IC50 6.82 μL/mL), and antilipase (IC50 1.08 μL/mL) effects. The EO also demonstrated high antibacterial activity with the highest susceptibility observed for Staphylococcus aureus with 95.7% inhibition. The EO was shown to exhibit strong inhibitory activity against Candida albicans (MIC 0.47 μL/mL). The EO was also shown to possess strong antidermatophyte activity against Microsporum canis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum (EC50 0.05–0.06 μL/mL). The high antioxidant, enzyme inhibitory, and antimicrobial potentials of the EO can, therefore, be correlated with its high content of monoterpenes, especially carvacrol, as shown by its comparable bioactivities indicators results. This study provided new insights into the composition and bioactivities of LP EO. Our finding revealed evidence that LP EO makes a valuable natural source of bioactive molecules showing substantial potential as antioxidant, neuroprotective, antihyperlipidemic, and antimicrobial agents. This study demonstrates, for the first time, that LP EO might be useful for further investigation aiming at integrative CAM and clinical applications in the management of dermatophytosis, Alzheimer’s disease, and obesity.

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“…Another two endemic species are L. pinnata and L. pubescens collected in Spain and Yemen, were studied by Argentieri et al . and Al Badani et al . Both were carvacrol chemotypes with a variable amount of carvacrol methyl ether and caryophyllene oxide as other main compounds.…”

Section: Essential Oils: Very Old ‘Guys’ With Great Prospectsmentioning

confidence: 99%

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Napoli

Siracusa

Ruberto

2020

Chemistry & Biodiversity

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Lamiaceae is one of the largest families of flowering plants comprising about 250 genera and over 7,000 species. Most of the plants of this family are aromatic and therefore important source of essential oils. Lamiaceae are widely used as culinary herbs and reported as medicinal plants in several folk traditions. In the Mediterranean area oregano, sage, rosemary, thyme and lavender stand out for geographical diffusion and variety of uses. The aim of this review is to provide recent data dealing with the phytochemical and pharmacological studies, and the more recent applications of the essential oils and the non‐volatile phytocomplexes. This literature survey suggests how the deeper understanding of biomolecular processes in the health and food sectors as per as pest control bioremediation of cultural heritage, or interaction with human microbiome, fields, leads to the rediscovery and new potential applications of well‐known plants.

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Variations in Essential Oil Compositions of Lavandula pubescens (Lamiaceae) Aerial Parts Growing Wild in Yemen

Cited by 12 publications

References 19 publications

Essential Oil Analysis and Antimicrobial Evaluation of Three Aromatic Plant Species Growing in Saudi Arabia

Essential Oil Analysis and Antimicrobial Evaluation of Three Aromatic Plant Species Growing in Saudi Arabia

Downy Lavender Oil: A Promising Source of Antimicrobial, Antiobesity, and Anti‐Alzheimer’s Disease Agents

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

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