Variations in mitochondrial DNA control region among Malay and Chinese subpopulations (sequence 16000–16200)

Ishar, Seri Mirianti; Parameswaran, Kiroobhashini; Masduki, Nur Safrina; Din, Rus Dina Rus

doi:10.1080/24701394.2019.1687693

Cited by 1 publication

(1 citation statement)

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“…Nevertheless, there are few limitations in these studies that drives the urge to conduct an improved genetic research in future. Ishar et al (2019) mentioned that more variations needed to be analyzed to increase the discrimination power of SNP markers. Besides that, low number of samples can lead false positive results by giving higher percentage of haplogroup frequencies.…”

Section: Discussionmentioning

confidence: 99%

Perspectives on Ancestral Lineages and Genetic Markers of Malay Population in Peninsular Malaysia

PARTHIPAN¹,

ISHAR²

2022

JSKM

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The Malay people are the majority in Peninsular Malaysia, but their population structure and genetic profile remain poorly studied. The exposure to the origins of Malays and their sub-ethnic groups is vital prior to study about their genetic profiles as it can narrow down the haplogroups of their ancestral lineages. In this review, we have highlighted theories related to the origin of Malays from Yunnan, New Guinea, Taiwan, Sundaland, Nusantara and the theory of Bani Jawi. Nevertheless, these theories were established based on speculations without evidence. Despite the theories developed, the migration of Malay population is more prominent during the era of Malacca Sultanate. The trading activities and seafaring way of life had welcomed various ethnic groups in Peninsular Malaysia which formed a part of the Malay population today. Thus, the origin of major sub-ethnic groups of Malay population are discussed in this paper. The origin of Malay community has a key relationship with modern genomic field that was conducted through mitochondrial DNA analysis. Human identification in forensic application is tedious due to the need for sequencing whole DNA profile of Malay population. Therefore, identification of specific genetic markers for Malay population is vital to facilitate forensic investigation. We gathered data by systematically searched with Google Scholar, Pubmed, Science Direct with advanced search builder for papers titles with Malay population and genetic markers. This study shed some light on the mitochondrial DNA markers of indigenous people and Malay population in Peninsular Malaysia which can be used in future prospects.

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Section: Discussionmentioning

confidence: 99%