Variations in population health status: results from a United Kingdom national questionnaire survey

Kind, Paul; Dolan, Paul; Gudex, Claire; Williams, Alan

doi:10.1136/bmj.316.7133.736

Cited by 961 publications

(834 citation statements)

References 16 publications

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“…Hence, this descriptive system contains 243 combinations or index values for health states [9]. We used the value set based on the main survey from the EuroQol group [10,11], which has been validated for this patient population [12]. Total score range is from -0.594 to 1, where 1 corresponds to perfect health, and 0 to death.…”

Section: Eq-5dmentioning

confidence: 99%

Recovery of muscle strength after microdiscectomy for lumbar disc herniation: a prospective cohort study with 1-year follow-up

et al. 2011

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Background Surgery has not been proven to be a better treatment option than non-operative management for limb paresis due to lumbar disc herniation. For the patients it will still be a concern, whether they will regain full strength after the operation or not. Methods A prospective cohort study of 91 patients with preoperative paresis due to disc herniation with 1-year follow up was carried out. The primary outcome was muscle strength in affected limb, and the secondary outcome was self-reported symptoms on back and leg pain, disability, health related quality of life, general health and working capability. Results Seventy-five percent of patients had no paresis 1 year after the operation. The severity of the paresis was the only predictor for persistent paresis. Preoperative duration of the paresis did not influence the rate of full recovery. Non-recovery was associated with inferior outcomes and higher risk for reduced working capability. Conclusions The majority of patients with paresis were fully recovered 1 year after microdiscectomy for lumbar disc herniation. If the paresis was severe at baseline, there was a four times higher risk for non-recovery. Patients who did not recover had significantly worse outcomes.

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Section: Eq-5dmentioning

confidence: 99%

Recovery of muscle strength after microdiscectomy for lumbar disc herniation: a prospective cohort study with 1-year follow-up

et al. 2011

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“…The coefficient of variation for influenza deaths was assumed to be the same as that for hospitalisation. The average age of pregnancy was assumed to be 29 years [29], with the quality-adjusted life years lost due to influenza calculated using mortality rates by age group and health-related quality of life scores from the general population [30]. Hence we estimated that the death of an infant and a pregnant mother result in 20.0 and 23.8 QALYs lost respectively.…”

Section: Deaths the Hes Database Recorded 28 Deaths Between 2001 Andmentioning

confidence: 99%

“…For hospital and ICU admissions, quality of life weights of 0.65 and 0.52 respectively were used, based on an expert consultation convened by the Institute of Medicine [44]. Given the lack of information about uncertainty around these estimates, they were varied over symmetrical triangular distributions up to a maximum quality of life weight of 0.87 (the average quality of life for someone aged 20-39 years old [30]. The estimated length of stay for influenza hospitalisations was 3.68 days (95% CI 2.91 -4.45), using admissions for influenza-like respiratory illnesses in HES regressed against respiratory pathogens in LabBase2 (see Supplement S1).…”

Section: Deaths the Hes Database Recorded 28 Deaths Between 2001 Andmentioning

confidence: 99%

The cost-effectiveness of vaccinating pregnant women against seasonal influenza in England and Wales

Jit¹,

Cromer²,

Baguelin³

et al. 2010

Vaccine

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We assessed the cost-effectiveness of vaccinating pregnant women against seasonal influenza in England and Wales, taking into account the timing of vaccination relative to both the influenza season and trimester of pregnancy. Women were assumed to be vaccinated in their second or third trimester. Vaccination between September and December was found to have an incremental cost-effectiveness ratio of £23,000 per QALY (95% CI £10,000 -£140,000) if it is assumed that infants are partially protected through their mothers, and of £29,000 per QALY gained (95% CI £14,000 -£200,000) if infants are not protected. If some vaccine protection lasts for a second season, then the ratio is only £15,000 per QALY gained (95% CI £6,000 -£91,000). Most of the benefit of vaccination is in preventing symptomatic episodes, regardless of health care resource use. Extending vaccination beyond December is unlikely to be cost-effective unless there is good protection into a second influenza season. Key sources of uncertainty are the cost of vaccine delivery and the quality of life detriment due to a clinically apparent episode of confirmed influenza. The cost of vaccine purchase itself is relatively low.3

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“…The EQ-5D is a simple measure to subjectively describe and value health status [6-8] . It has been used to measure and compare the health status of general population samples in various countries [9-15]. The EQ-5D consists of two parts, the EQ-5D descriptive system and the visual analogue scale (EQ-VAS).…”

Section: Introductionmentioning

confidence: 99%

Health status of the advanced elderly in six european countries: results from a representative survey using EQ-5D and SF-12

König

Heider

Lehnert

et al. 2010

Health Qual Life Outcomes

109

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Background Due to demographic change, the advanced elderly represent the fastest growing population group in Europe. Health problems tend to be frequent and increasing with age within this cohort. Aims of the study To describe and compare health status of the elderly population in six European countries and to analyze the impact of socio-demographic variables on health. Methods In the European Study of the Epidemiology of Mental Disorders (ESEMeD), representative non-institutionalized population samples completed the EQ-5D and Short Form-12 (SF-12) questionnaires as part of personal computer-based home interviews in 2001-2003. This study is based on a subsample of 1659 respondents aged ≥ 75 years from Belgium (n = 194), France (n = 168), Germany (n = 244), Italy (n = 317), the Netherlands (n = 164) and Spain (n = 572). Descriptive statistics, bivariate- (chi-square tests) and multivariate methods (linear regressions) were used to examine differences in population health. Results 68.8% of respondents reported problems in one or more EQ-5D dimensions, most frequently pain/discomfort (55.2%), followed by mobility (50.0%), usual activities (36.6%), self-care (18.1%) and anxiety/depression (11.6%). The proportion of respondents reporting any problems increased significantly with age in bivariate analyses (age 75-79: 65.4%; age 80-84: 69.2%; age ≥ 85: 81.1%) and differed between countries, ranging from 58.7% in the Netherlands to 72.3% in Italy. The mean EQ VAS score was 61.9, decreasing with age (age 75-79: 64.1; age 80-84: 59.8; age ≥ 85: 56.7) and ranging from 60.0 in Italy to 72.9 in the Netherlands. SF-12 derived Physical Component Summary (PCS) and Mental Component Summary (MCS) scores varied little by age and country. Age and low educational level were associated with lower EQ VAS and PCS scores. After controlling for socio-demographic variables and reported EQ-5D health states, mean EQ VAS scores were significantly higher in the Netherlands and Belgium, and lower in Germany than the grand mean. Conclusions More than two thirds of the advanced elderly report impairment of health status. Impairment increases rapidly with age but differs considerably between countries. In all countries, health status is significantly associated with socio-demographic variables.

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Variations in population health status: results from a United Kingdom national questionnaire survey

Cited by 961 publications

References 16 publications

Recovery of muscle strength after microdiscectomy for lumbar disc herniation: a prospective cohort study with 1-year follow-up

Recovery of muscle strength after microdiscectomy for lumbar disc herniation: a prospective cohort study with 1-year follow-up

The cost-effectiveness of vaccinating pregnant women against seasonal influenza in England and Wales

Health status of the advanced elderly in six european countries: results from a representative survey using EQ-5D and SF-12

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