“…Wheat, as one of the most important food crops, anatomically composed of bran, germ, and endosperm. Compared with the refined wheat flour, whole wheat flour milling by whole grain wheat (WGW) retained the bran layer, which is rich in protein, vitamins, dietary fiber, and other phytochemicals (phenolic acids, flavonoids, polyphenols, alkylresorcinols, arabinoxylans, and others) ( [1]; Tian et al, [2]; Tian et al, [3]). A large number of studies have been verified that polyphenol compounds have the potential of antioxidation, anti-inflammatory, and antiproliferation capacity ( [4]; Kundu, & Sethi, [5,6]), which is a benefit for reducing the risks of chronic diseases (e.g., cardiovascular disease, obesity, and type II diabetes) and cancers (Wu et al, [7]).…”