Varicella-Zoster Virus

Creed, Rosella; Satyaprakash, Anita

doi:10.3109/9781420073133-6

Cited by 5 publications

(14 citation statements)

References 68 publications

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“…Approximately 1 million cases of herpes zoster are diagnosed annually in the United States. 1 Persons with a history of primary varicella infection have a 10% to 20% lifetime chance of developing herpes zoster infection. 1 Zoster most frequently occurs in the elderly as cellmediated immunity to VZV declines.…”

Section: Discussionmentioning

confidence: 99%

A 55-Year-Old Man With a Painful Rash on the Sole of His Foot

Vangipuram

Tyring

2017

JAMA

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A 55-year-old man with hypertension and hypercholesterolemia presented to the clinic with a 6-day history of a painful rash on the sole of his right foot. He described the pain as akin to stepping on a sharp object and characterized it as moderately intense, sharp, continuous, and without radiation. After first noticing the pain, he had examined the inside of his boot but did not identify anything that would account for the tenderness. He reported no fevers, chills, or malaise. He denied history of human immunodeficiency virus (HIV), hepatitis, chickenpox, or recurrent infections. His medications included amlodipine, hydrochlorothiazide, and ezetimibe. He worked outdoors for an oil drilling company. He denied recent travel out of the country. Physical examination revealed 2-to 3-mm grouped vesicles on an erythematous base in a discrete area of the sole of the right foot (Figure ) and no additional rashes elsewhere on the body. Vesicular fluid was sent for analysis. Figure. Left, Grouped vesicles on sole of patient's right foot. Right, Closer view of vesicles. WHAT WOULD YOU DO NEXT? A. Obtain blood cultures B. Initiate antiviral therapy with valacyclovir C. Prescribe an oral antihistamine agent D. Prescribe a topical corticosteroid cream Clinical Review & Education JAMA Clinical Challenge

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Section: Discussionmentioning

confidence: 99%

A 55-Year-Old Man With a Painful Rash on the Sole of His Foot

Vangipuram

Tyring

2017

JAMA

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“…Because it is uncommon for HZ to recur in otherwise healthy individuals,1 studies with the attenuated strain of the varicella zoster virus were completed in order to boost the immunity of persons without a history of HZ in order to prevent the disease and/or its complications.…”

Section: Commentarymentioning

confidence: 99%

Vaccination of older adults against herpes zoster is safe and effective

Tyring¹

2013

Evid Based Med

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“…[ 3 ] The rash appears first on the chest, back and face and then spreads over the entire body. [ 4 ] This infection is established when the virus in the respiratory droplets or vesicular fluid from an infected person comes in contact with the mucosa of respiratory tract of an unaffected person. [ 5 ] Since the introduction of varicella immunization in 1995, the number of cases have been declined.…”

Section: Introductionmentioning

confidence: 99%

Herpes zoster of orofacial region

Dosi

Chawla

Barkalle

et al. 2021

Journal of Oral and Maxillofacial Pathology

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Herpes zoster (HZ) is a viral disease which is primarily caused by the nerve tissue, but its treatment necessitates a multidisciplinary approach. Varicella zoster virus (VZV) is a DNA virus that causes both primary and recurrent infection. HZ, also known as shingles, is a unique condition induced by VZV reactivation. Neuropathic pain, headache, malaise and sleep disruption are all prodromal symptoms in such cases. HZ generates a pruritic, localized and vesicular rash that is usually unilateral. Individuals who are immunocompromised as a result of disease or receiving any treatment are also at increased risk, regardless of their age. HZ and its sequelae set a major strain on patient's caregivers, health-care system and business. Despite recent advances, prevention and treatment of HZ, consequences remain a therapeutic challenge. This is a case report of HZ infection in a 56-year-old female patient who was managed with comprehensive medical treatment.

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Varicella-Zoster Virus

Cited by 5 publications

References 68 publications

A 55-Year-Old Man With a Painful Rash on the Sole of His Foot

A 55-Year-Old Man With a Painful Rash on the Sole of His Foot

Vaccination of older adults against herpes zoster is safe and effective

Herpes zoster of orofacial region

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