Varicella-Zoster Virus Infection and Osteomyelitis of the Skull

Sommer, Taylor; Karsy, Michael; Driscoll, Meghan; Jensen, Randy L.

doi:10.1016/j.wneu.2018.04.194

Cited by 11 publications

(11 citation statements)

References 10 publications

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“…Varicella zoster also have a rare association with erythema multiforme [20]. Few cases of acute calvarial osteomyelitis or rhabdomyolysis associated with VZV infection or reactivation were reported [21] [22].…”

Section: Discussionmentioning

confidence: 99%

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Chen,

Wang,

Yan

2024

Preprint

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Background:Varicella (chicken pox), which caused by the varicella-zoster virus(VZV), is usually self-limiting and benign. However, VZV can lead to significant and serious complications, especially in immunocompromised patients or accompanied by other pathogens infection. HPS caused by varicella-zoster and influ B virus co-infection is rare. Case presentation:A 15-years-old boy was admitted to our hospital because of general rash, severe back and low back pain. CT scan revealed pneumonia in left upper lobe. Initial blood tests showed normal blood WBC and PLT, mild liver dysfunction, enhanced D-dimer and myocardial enzyme. However, after 4-days treatment of acyclovir, antibiotics, and analgesic therapy, his pain did not relieved and fever developed. At the same time, hyperferritinemia, abrupt reduction on blood WBC and PLT count were observed. Virus-associated hemophagocytic syndrome (VHAS)was confirmed.Then, intravenous drip dexamethasone(10mg/day) and gamma globulin(10mg/day) were administrated. He recovered completely at last. Conclusions:Disseminated Varicella which was accompanied by influenza B virus and bacteria infection is infrequent. Disseminated varicella may cause significant morbidity and even mortality in immunocompromised patients. Hemophilic syndrome induced by duel-virus and bacteria infection is limited and usually fetal.Anti-bacterial therapy, early identification of haemophilus syndrome and timely administration of glucocorticoids and gamma globulin are the key links of treatments.

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Section: Discussionmentioning

confidence: 99%

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Chen,

Wang,

Yan

2024

Preprint

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“…Staphylococcal or streptococcal toxic shock syndrome, osteomyelitis, necrotising fasciitis (previously known as "varicella gangrenosa", caused by exotoxin of group A β-haemolytic streptococci, which lead to an extensive local tissue destruction) belong to the group of more serious bacterial complications [13,17,18]. Casuistical varicella complication by calvaria osteomyelitis was described by Sommer et al [19].…”

Section: Discussionmentioning

confidence: 99%

Bullous varicella in a preschool-aged patient

Pavlyshyn¹,

Horishna²

2019

polp

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Varicella (chickenpox) is a highly contagious febrile rash illness caused by primary infection with Varicella zoster virus (VZV/HHV-3), which is one of the eight human herpes viruses, transmitted by respiratory contact with aerosolised respiratory secretions and blister secretions or by direct contact with them. The typical course of varicella in immunocompetent unvaccinated children is generally mild and uncomplicated. A clinical case of atypical bullous varicella in a preschool child, who was thought to be immunocompetent, was consequently analysed. The disease had typical moderate course, aggravated with characteristic skin syndrome. Hospitalisation and adequate, timely treatment of the patient according to modern guidelines led to his fast, complete recovery and showed the effectiveness of such therapy.

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“…The vesicles are most commonly seen on the ear but may also be present on the affected area's tongue, cheek, or scalp. There is a variant known as zoster sine herpete, in which the patient presents with severe pain and facial paralysis but no vesicular rash in the affected area and is almost indistinguishable from Bell's Palsy (facial paralysis without inflammation) [ 6 ]. Ramsay Hunt syndrome is the second most occurring cause of non-traumatic facial nerve paralysis of the periphery.…”

Section: Introductionmentioning

confidence: 99%

“…Ramsay Hunt syndrome is the second most occurring cause of non-traumatic facial nerve paralysis of the periphery. Before 1986, the incidence of peripheral facial paralysis was estimated, and 4.5% to 8.9% of individuals with peripheral facial paralysis had VZV [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Ramsay Hunt Syndrome: An Introduction, Signs and Symptoms, and Treatment

Goswami¹,

Gaurkar²

2023

Cureus

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Ramsay Hunt syndrome is the complication of the virus varicella-zoster and the infection caused by it, which shows apparent geniculate ganglion involvement. This article discusses the etiology, epidemiology, and pathology of Ramsay Hunt syndrome. Clinically it may be presented as a vesicular rash on the ear or even in the mouth, pain in the ear, and facial paralysis. Some other rare symptoms may also be present, which are also discussed in this article. Skin involvement is also seen in some cases as patterns due to anastomoses between cervical and cranial nerves. This article provides an overview of how the varicella-zoster virus causes facial paralysis and other neurological symptoms. Knowing about this condition and its clinical features is essential to make an early diagnosis and, thus, provide a good prognosis. A good prognosis is required to reduce the nerve damage, prevent further complications, and start an early therapy of acyclovir and corticosteroid. This review also presents a clinical picture of the disease and its complications. The incidence of Ramsay Hunt syndrome has gradually decreased over time because of the development of the varicella-zoster vaccine and better health facilities. The paper also talks about how the diagnosis of Ramsay Hunt syndrome is made and the various treatment options available. Facial paralysis in Ramsay Hunt syndrome presents differently than Bell's Palsy. If not treated for too long, it may cause permanent muscle weakness and may also cause a loss of hearing. It may be confused with simple herpes simplex virus outbreaks or contact dermatitis.

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Varicella-Zoster Virus Infection and Osteomyelitis of the Skull

Cited by 11 publications

References 10 publications

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Virus-associated hemophagocytic syndrome caused by influ B and varicella-zoster virus co-infection

Bullous varicella in a preschool-aged patient

Ramsay Hunt Syndrome: An Introduction, Signs and Symptoms, and Treatment

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