Varicose veins arising from the pelvis due to ovarian vein incompetence

Hobbs, J. T.

doi:10.1111/j.1368-5031.2005.00631.x

Cited by 66 publications

(74 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They may be the consequence of chronic pelvic congestion, portal hypertension or obstructive pelvic lesions. Ovarian vein incompetence can lead to varicosities in the vulva and legs (Hobbs 2005).…”

Section: Varicose Veinsmentioning

confidence: 99%

Non‐Infective Cutaneous Conditions of the Vulva

Neill

Lewis

2009

Ridley's the Vulva

View full text Add to dashboard Cite

Section: Varicose Veinsmentioning

confidence: 99%

Non‐Infective Cutaneous Conditions of the Vulva

Neill

Lewis

2009

Ridley's the Vulva

View full text Add to dashboard Cite

“…Unilateral or bilateral ovarian vein incompetence can cause pelvic congestion syndrome, which induces chronic pain, irritable bladder, dysfunction of the pelvic organs, or vulval varices and varicose veins in the lower limbs (1,5,7). Our previous study demonstrated that chronic prostatitis and stress urinary incontinence were related to the existence of vena cava reflux caused by tricuspid regurgitation (28).…”

mentioning

confidence: 99%

<b>Naftopidil improves locomotor activity and urinary frequency in rats with pelvic venous </b><b>congestion </b>

Sugaya¹,

Nishijima²,

Kadekawa³

et al. 2016

Biomed. Res.

View full text Add to dashboard Cite

The α1D/A receptor antagonist, naftopidil, inhibits micturition reflex by acting on various different sites. We examined the effects of naftopidil on bladder activity and changes in the induced urinary frequency using female rats with pelvic venous congestion (PC). Twenty-four female rats were divided into sham, PC, and PC/naftopidil groups. After anesthetizing rats in the PC and PC/naftopidil groups, the bilateral common iliac veins and uterine veins were ligated. Rats in the sham and PC groups were fed a standard diet, while rats in the PC/naftopidil group were fed diets containing 0.04% naftopidil. After 4 weeks of treatment, locomotor activity, urinary nitric oxide metabolites (NOx), continuous cystometry, and plasma monoamine measurements were performed. PC rats exhibited a decrease of locomotor activity, a shorter interval between bladder contractions on continuous cystometry, and decreased urinary NOx and plasma serotonin levels than the sham rats. The PC/naftopidil rats exhibited an increase of locomotor activity, a longer interval between bladder contractions, and increased urinary NOx and plasma serotonin levels. Therefore, naftopidil might improve bladder dysfunction induced by pelvic venous congestion due to several actions in the central nervous system and bladder tissue, as well as acting as an α1 blocker to cause pelvic venous dilation.Unilateral or bilateral ovarian vein incompetence can cause pelvic congestion syndrome, which induces chronic pain, irritable bladder, dysfunction of the pelvic organs, or vulval varices and varicose veins in the lower limbs (1, 5, 7). Our previous study demonstrated that chronic prostatitis and stress urinary incontinence were related to the existence of vena cava reflux caused by tricuspid regurgitation (28). When we examined a female case with pelvic congestion syndrome using external iliac venography, we found that pelvic venous congestion occurred with tricuspid regurgitation and without pelvic venous valves (25). Our previous studies have also demonstrated that ligation of the bilateral common iliac veins in male rats or ligation of the bilateral common iliac veins and uterine veins in female rats induced changes in the urinary frequency and low locomotor activity (30). As compared to the intact rats, these surgically altered rats exhibited a bladder blood flow decrease that was about 80% of the flow in the intact bladder. Therefore, pelvic venous congestion may be one of the causes of pelvic ischemia, and might be related to several lower urinary tract symptoms/diseases. When examining hypertension, the relevance of lower urinary tract symptoms and their association with hypertension need to be taken into consideration. Spontaneously hypertensive rats have been shown to have a significantly lower bladder capacity and voiding volume (24), and these rats also exhibit

show abstract

“…If the symptoms persist for more than 12 weeks postpartum, the varix can be treated with sclerotherapy [10]. Although in some mild cases successful treatment can be achieved with either local excision or sclerotherapy [5,6,10,11], a laparoscopic ligation of the incompetent veins can be considered in patients with pelvic congestion syndrome [11]. In the author's case, the patient's vaginal varix resolved after 6 weeks postpartum without any additional treatment.…”

Section: Discussionmentioning

confidence: 99%

“…In this case, the patient recognized the lesion growing in the later months of gestation. Most genital varices are asymptomatic, but a few are associated with severe local discomfort, accompanied by spontaneous vaginal bleeding, or with pelvic pain as part of the so-called "pelvic congestion syndrome"; pelvic pain, dyspareuria, dysmenorrhea, dysuria, vulvar and perivulvar varices [5,6]. The vaginal varix can be ruptured from trauma, leading to a vaginal hematoma or thrombus during the second stage of labor.…”

Section: Discussionmentioning

confidence: 99%

A case of vaginal varix during pregnancy

Kim

Lee

2012

Korean J Obstet Gynecol

View full text Add to dashboard Cite

Vaginal varix during pregnancy is a rare condition. Only a few cases have been reported in the literature. Most vaginal varices are asymptomatic, but some are associated with a sense of local mass, or severe discomfort and spontaneous vaginal bleeding. A 32-year-old woman was admitted for acute spontaneous vaginal bleeding at 37+6 weeks' gestation. Upon pelvic inspection, we observed dilated vascular structure on the suburethral vaginal wall, and the trans-labial ultrasound imaging revealed a blood fl ow along the vaginal area, confi rming the presence of a vaginal varix. Instead of a normal delivery, we performed a Cesarean section to prevent the potential risk of the profuse vaginal bleeding. The postoperative course was uneventful, and the mass spontaneously resolved 6 weeks after the delivery. The authors believe that this case of vaginal varix found during pregnancy is the fi rst documented case in Korea. Keywords:Vaginal varicose veins; Pregnancy; Hemorrhage CASE REPORT Received: 2011. 7.20. Revised: 2011. 9. 7. Accepted: 2011 Vulvar varices are reported in 4% of women [1], and most of them may be secondary to pregnancy from other anatomical and pathological diseases such as Klippel-Trenaunay-Weber syndrome or pelvic congestion syndrome. However, the vaginal varices, located in the vaginal and periurethral wall, are reported less frequently. Vaginal varix in non-pregnant women does not exhibit a serious threat; however, during pregnancy, the spontaneous laceration of the vaginal varix can cause significant blood loss. Therefore, an obstetrician should be aware of its clinical importance. We report a case of vaginal varix during pregnancy and its clinical features for the fi rst time in Korea. Case ReportA 32-year-old multiparous woman who was a nonsmoker with no signifi cant medical history visited the department of obstetrics and gynecology because of acute spontaneous vaginal bleeding. The woman was at 37+6 week of gestation with the fetus having a cephalic presentation. The pregnancy had been normal during the prenatal check 2 weeks ago, when the patient experienced cough and rhinorrhea. The patient recognized the lesion had been enlarged as the pregnancy continued few months into the conception. We found the vaginal bleeding and performed a pelvic inspection by spreading the labia minor with two fingers, and were surprised to find a strawberry sized vascular lesion on the suburethral vaginal wall, obstructing the vaginal lumen (Fig. 1). We detected a bleeding point on the varix. On the visit, the patient's vital signs were stable and the fetal heart rate pattern on non-stress test was reactive. The sonographic examination revealed a mixed echogenic mass that was 2.3 × 2.7 cm in size at the anterior vaginal wall area. Maximal systolic and diastolic velocity at 21.7 cm/sec and 12.8 cm/sec, respectively, was found using Power Doppler sonography, and the resistance index was 0.41 (Fig. 2). The fetus grew normally according to the gestational age. Also, the placenta showed left lateral attachment and the am...

show abstract

Varicose veins arising from the pelvis due to ovarian vein incompetence

Cited by 66 publications

References 17 publications

Non‐Infective Cutaneous Conditions of the Vulva

Non‐Infective Cutaneous Conditions of the Vulva

<b>Naftopidil improves locomotor activity and urinary frequency in rats with pelvic venous </b><b>congestion </b>

A case of vaginal varix during pregnancy

Contact Info

Product

Resources

About