Varied presentations of unilateral lung hypoplasia and agenesis: a report of four cases

Thomas, Raji; Lathif, H C; Sen, Sudipta; Zachariah, Ninan; Chacko, Jacob

doi:10.1007/s003830050447

Cited by 23 publications

(18 citation statements)

References 2 publications

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“…5 Nevertheless, some adult patients may present with repeated pulmonary infections and wheezing. 6,7 Plain radiographs demonstrate decreased aeration of the affected hemithorax and a small thoracic cage. A common finding is a shift of the mediastinum to the side of the hypoplasia, accentuated during inspiration due to increased compensatory ventilation of the other lung.…”

Section: Discussionmentioning

confidence: 99%

Unilateral Primary Lung Hypoplasia Diagnosed in Adulthood

2013

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Unilateral primary pulmonary hypoplasia is rare in adulthood. It is usually present in the neonatal period or in early childhood, and is characterized by a decreased number of bronchial segments and decreased/absent alveolar air space. Most patients have recurrent episodes of wheezing or pneumonia and severe respiratory distress leading to chronic respiratory failure, whereas some patients may occasionally be asymptomatic. Herein, we present a case of left lung hypoplasia in an asymptomatic 28-year-old male, who was admitted to the hospital for further investigation of an abnormal result on a chest radiograph that was obtained as part of a health evaluation for military service. A thorough workup, including imaging modalities and bronchoscopy, disclosed a hypoplastic left lung, which had gone undiagnosed for 25 years. Embryological, clinical, and diagnostic aspects are briefly discussed.

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Section: Discussionmentioning

confidence: 99%

Unilateral Primary Lung Hypoplasia Diagnosed in Adulthood

2013

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“…4,5 Thomas et al suggested that CT is more useful than bronchography in assessing the hypoplastic lung, especially for the purposes of its surgical removal. 6 Radiographic findings in cases of hypoplasia are similar and characterized principally by almost total absence of aerated lung in one hemi thorax. The markedly reduced volume is indicated by approximation of ribs, elevation of ipsilateral diaphagram and shift of the mediastinum.…”

Section: Discussionmentioning

confidence: 60%

Unilateral Lung Hypoplasia Presenting in Adolescence: A Case Report

Paul¹,

Bharti²,

Kazal³

2015

jemds

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Pulmonary hypoplasia is a rare congenital anomaly, which is frequently associated with other congenital anomalies. Most patients have recurrent episodes of wheezing or pneumonia and severe respiratory distress leading to chronic respiratory failure whereas some may be asymptomatic. Although it is usually diagnosed in infancy and childhood, some cases do not show any symptoms until the adolescent ages. In adolescents and adults with unilateral hypolucent lung, pulmonary hypoplasia should always be kept in mind.

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“…Some patients may present months to years later with repeated pulmonary infections and wheezing. 15 The differential diagnosis of respiratory distress in the newborn associated with marked opacification of one side of the thorax on radiograph includes atelectasis, congenital diaphragmatic hernia (CDH), congenital cystic adenomatoid malformation (CCAM), pulmonary sequestration, chylothorax, pulmonary hypoplasia, bronchogenic cyst, and a chest tumor (e.g., neuroblastoma, teratoma, fibrosarcoma). In a right-sided CDH, there may be opacification of the right hemithorax if the liver is occupying that space.…”

Section: Discussionmentioning

confidence: 99%