Vascular Access

Himmelfarb, Jonathan; Dember, Laura M.; Dixon, Bradley S.

doi:10.1016/b978-1-4160-0158-4.50021-5

Cited by 4 publications

(4 citation statements)

References 192 publications

(301 reference statements)

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“…Las fístulas se pueden formar con una anastomosis de la arteria venosa de extremo a lado o de lado a lado. Es preferible utilizar la extremidad distal para la colocación inicial del acceso y utilizar el brazo no dominante para limitar la discapacidad funcional del paciente, por lo tanto, si los vasos del antebrazo parecen adecuados, se deberá crear una fístula como acceso inicial (Himmelfarb, Dember, & Dixon, 2005). Debido a que la calidad de la vena es crítica para la creación de una fístula, se deben hacer todos los esfuerzos posibles para proteger las venas en la extremidad.…”

Section: Fístula Arteriovenosaunclassified

“…Existen otras circunstancias en donde se han construido accesos de tipo heróicos, como por ejemplo el injerto de collar que conecta la arteria axilar o subclavia con la vena yugular o subclavia contralateral; y el injerto de interposición arterial, en el cual se secciona alguna arteria como la subclavia, femoral o braquial, y se inserta un bucle de material del injerto conectando los extremos distal y proximal de la arteria. (Himmelfarb, Dember, & Dixon, 2005)…”

Section: Injertounclassified

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Dialisis

Salazar-Fuentes

Vázquez-García

Estrada-Villegas

et al. 2021

ICBI

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Se expone la diálisis como un método de purificación de coloides, teniendo una aplicación especial en el tratamiento de pacientes con insuficiencia renal. Se presentan algunos antecedentes, referencias geográficas en México, y el proceso para llevar a cabo esta técnica de superficie, una muestra del equipo de purificación constituido, así como los cuidados necesarios del paciente. Se muestra como objetivo el difundir el conocimiento básico de esta técnica en aplicaciones médicas reales. Se han abordado temas importantes como el inicio no programado en diálisis, los tipos de diálisis como tratamiento en la disfunción renal y la importancia de informar y educar al paciente antes de su inclusión en las diferentes modalidades de su tratamiento renal sustitutivo.

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Section: Fístula Arteriovenosaunclassified

Section: Injertounclassified

Dialisis

Salazar-Fuentes

Vázquez-García

Estrada-Villegas

et al. 2021

ICBI

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“…EPO is important for the treatment of renal anemia, and correction of anemia by the drug improves the quality of life in patients with renal failure. However, EPO can contribute to stenosis and occlusion of vascular access for hemodialysis by promoting hyperplasia of vascular wall and thrombosis (Himmelfarb et al, 2005;Lee et al, 2009). Some studies in vivo have shown that long term EPO therapy may not increase the risk of stenosis of the arteriovenous fistula.…”

Section: Introductionmentioning

confidence: 99%

“…Some studies in vivo have shown that long term EPO therapy may not increase the risk of stenosis of the arteriovenous fistula. (De Marchi et al,1997) Vascular access failure is a major cause of morbidity and hospitalization in hemodialysis populations worldwide (Himmelfarb et al, 2005;Roy-Chaudhury et al, 2006). However, no pharmacological approach to avoid the EPO-related adverse reaction were developed until present time.…”

Section: Introductionmentioning

confidence: 99%

Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells

Kaneda

Tsuruoka

Fujimura

2010

European Journal of Pharmacology

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Erythropoietin (EPO) directly stimulates the proliferation of vascular smooth muscle cells, and this is believed to be one of the mechanisms of vascular access failure of hemodialysis patients. However, precise mechanisms of the EPO-induced proliferation of vascular smooth muscle cells are not certain. HMG-CoA reductase inhibitors (statins) are primarily used to reduce cholesterol levels, but also exert other effects, including reno-protective effects. We evaluated the effect of several statins with various hydrophilicities on the EPO-induced proliferation of primary cultured rat vascular smooth muscle cells (VSMCs) in vitro. EPO significantly and concentration-dependently increased DNA synthesis as assessed by [³H]thymidine incorporation, cell proliferation as assessed by WST-1 assay, and activation of the p44/42MAPK pathway. Therapeutic doses of statins (pravastatin, simvastatin, atorvastatin and fluvastatin) in patients with hypercholesterolemia almost completely suppressed all of the EPO-induced effects in a concentration-dependent manner. Co-addition of mevalonic acid almost completely reversed the effects of statins. Statin alone did not affect the basal proliferation capacity of the cells. The effects were almost similar among the statins. We concluded that statins inhibited EPO-induced proliferation in rat VSMCs at least partly through their inhibition of HMG-CoA reductase activity. In the future, statins might prove useful for the treatment of EPO-induced hyperplasia of vascular access. Because the statins all showed comparable effects irrespective of their hydrophilicities, these effects might be a class effect.

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Hemodialysis

Langston¹

2011

Nephrology and Urology of Small Animals

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Vascular Access

Cited by 4 publications

References 192 publications

Dialisis

Dialisis

Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells

Hemodialysis

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