Vascular endothelium: A potential role in hiv infection and the pathogenesis of kaposi's sarcoma: Observations and speculations

The role of Kaposi sarcoma‐associated herpesvirus in the pathogenesis of Kaposi sarcoma

“…KS lesions are characterized by the presence of a rich inflammatory infiltrate involving monocytes, eosinophils and plasma cells in particular . Experimental evidence in support of a role for inflammatory cytokines in KS pathogenesis began to accumulate before the discovery of KSHV as the cause of this tumour . It is thought that the chronic immune activation seen in AIDS patients may exacerbate the oncogenic effects of KSHV.…”