Vascular Geometric Singularities, Hemodynamic Markers and Pathologies

Fluid-structure interaction in aortic dissections

“…In addition to the possibility of performing low-cost parametric studies, the advantage of these models lies in their access to velocity pressure and strain fields at any point and at any time of the cardiac cycle with a spatio-temporal resolution whose only limitation is the associated computation time. This precise mapping of blood flows thus allows an exact spatio-temporal quantification of all the physical quantities associated with their gradients, such as wall shear stress (WSS), time average wall shear stress (TAWSS) or vortical structures, for example, which are known to be a potential marker of the evolution of vascular pathologies (Deplano and Guivier-Curien, 2022). Some of these numerical simulations have so proposed to link the behavior of blood flow in aortic segments to the unfavorable evolution of vascular pathologies through elasto-hemodynamic indexes.…”