Introduction. PC6 or Neiguan is an acupoint broadly used in clinical acupuncture for the treatment of several diseases, mainly cardiovascular disorders. Nonetheless, its effects on cardiovascular physiopathology have not been fully described. Previous studies have shown that acupuncture at PC6 changes indices related to vascular distensibility of large and medium sized arterial vessels. It has been postulated that the PC6 stimulation modifies cardiovascular reflex responses. The aim of this study was to compare the effect of acupuncture point PC6 on cardiovascular variables in non smokers versus smokers.Subjects and methods. Systolic, diastolic, mean arterial pressures, heart rate an stroke volume were determined. These parameters were studied in a population divided into two groups constituted as follows : group A 15 non smoking subjects , 8 women aged 20 -30 years ( 23.8 ± 3.27, mean ± SD) and 7 males aged 20 -30 years ( 27 ± 3.6 , mean ± SD) , and group B 15 smokers, 10 women aged 20 -30 years ( 25.9 ± 3.5 , mean ± SD) and 5 men aged 20 -30 (24.6 ± 3.21 , mean ± SD). In each subject a 20 minute period was recorded. An 2.54 cm in lenght and 0.32 mm in diameter was manually inserted and keep in situ during 5 minutes. Segments were compared of these three registration periods: baseline 0-300 s, transacupuncture 301 -600, and posacupuncture 601 -1200 s.x Results. The main findings were as follows: significant increase in systolic pressure in both experimental groups and with both points left and right; significant increase in diastolyc pressure in both experimental groups with PC6 left; significant increase mean arterial pressure in both experimental groups with PC6 left; significant decrease in heart rate with PC6 right in both experimental groups, and PC6 left in the smokers group, significant increase in stroke volume with PC6 right or PC6 left in smokers and PC6 left in the non smoking group.
Conclusion.These findings suggest that manual stimulation of PC6 significantly modifies the parameters examined, and left or right PC6 produce distinct effects on the variables examined.