Vascular stents: Coupling full 3-D with reduced-order structural models

Avdeev, Ilya; Shams, Mir Zunaid

doi:10.1088/1757-899x/10/1/012133

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…The feasibility of the boundary condition was validated by our previous in vitro testing [Gu et al, 2005]. The stent was modeled by a general shell element, which has been verified by the study on the effects of different element types [Avdeev and Shams, 2010]. The tissue materials are assumed to be isotropic and homogeneous, although the artery and plaque have been shown to be anisotropic and viscoelastic [Loree et al, 1994;Salunke et al, 2001].…”

Section: Discussionmentioning

confidence: 97%

Arterial Wall Mechanics and Clinical Implications After Coronary Stenting: Comparisons of Three Stent Designs

Zhao

Froemming

2012

Int. J. Appl. Mechanics

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The goal of this work is to quantitatively assess the relationship between the reported restenosis rates and stent induced arterial stress or strain parameters through finite element method. The impact of three stent designs (Palmaz-Schatz stent, Express stent, and Multilink Vision stent) on the arterial stress distributions were characterized. The influences of initial stent deployment location, stent-tissue friction, and plaque properties on the arterial stresses were also investigated. Higher arterial stresses were observed at the proximal end of the plaque. The Multilink-Vision stent induced lesser stress concentrations due to the high stiffness of the Cobalt Chromium material and thinner strut thickness. The stent-induced arterial stress concentrations were positively correlated with the reported in-stent restenosis rates, with a correlation coefficient of 0.992. Stent deployment initiated at the center of the lumen led to less arterial stress variation, while deployment closer to the thinner edge of the plaque causes higher arterial stresses. The friction between the stent and tissue was found to contribute to larger stress alternations for the plaque only. Increased plaque stiffness resulted in a reduced arterial stress concentration and clinical restenosis rate. Results presented herein suggested that arterial stresses serve as a comprehensive index factor to predict the occurrence of in-stent restenosis, which will facilitate the new stent design and surgical planning.

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Section: Discussionmentioning

confidence: 97%

Arterial Wall Mechanics and Clinical Implications After Coronary Stenting: Comparisons of Three Stent Designs

Zhao

Froemming

2012

Int. J. Appl. Mechanics

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“…2. 2.2 Mesh and Boundary Conditions. The stent was meshed with 4-node general shell elements S4R, which has been validated by Avdeev et al [16]. Reduced 8-node brick elements C3D8R were used for the plaque and artery.…”

Section: Materials Modelsmentioning

confidence: 99%

On the Importance of Modeling Stent Procedure for Predicting Arterial Mechanics

Zhao

Gu²,

Froemming³

2012

Journal of Biomechanical Engineering

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The stent-artery interactions have been increasingly studied using the finite element method for better understanding of the biomechanical environment changes on the artery and its implications. However, the deployment of balloon-expandable stents was generally simplified without considering the balloon-stent interactions, the initial crimping process of the stent, its overexpansion routinely used in the clinical practice, or its recoil process. In this work, the stenting procedure was mimicked by incorporating all the above-mentioned simplifications. The impact of various simplifications on the stentinduced arterial stresses was systematically investigated. The plastic strain history of stent and its resulted geometrical variations, as well as arterial mechanics were quantified and compared. Results showed the model without considering the stent crimping process underestimating the minimum stent diameter by 17.2%, and overestimating the maximum radial recoil by 144%. It was also suggested that overexpansion resulted in a larger stent diameter, but a greater radial recoil ratio and larger intimal area with high stress were also obtained along with the increase in degree of overexpansion.

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