Pulmonary arterial dilatation associated with pulmonary hypertension may result in significant compression of local structures. Left main coronary artery and left recurrent laryngeal nerve compression have been described. Tracheobronchial compression from pulmonary arterial dilatation is rare in adults, and there are no reports in the literature of its occurrence in idiopathic pulmonary arterial hypertension. Compression in infants with congenital heart disease has been well described. We report 2 cases of tracheobronchial compression: first, an adult patient with idiopathic pulmonary arterial hypertension who presents with symptomatic left main bronchus compression, and second, an adult patient with Eisenmenger ventricular septal defect and right-sided aortic arch, with progressive intermedius and right middle lobe bronchi compression in association with enlarged pulmonary arteries.Keywords: bronchus compression, pulmonary arterial dilatation, complications. Pulmonary arterial dilatation in the setting of pulmonary hypertension is a common finding. 1 Extrinsic compression of the left main coronary artery and the left recurrent laryngeal nerve due to pulmonary arterial dilatation has been reported in the literature. [2][3][4][5] While uncommon, tracheobronchial compression due to pulmonary arterial dilatation is a well-known complication in infants with complex congenital heart disease and vascular rings. 6 In absent pulmonary valve syndrome, significant symptoms in early infancy are commonly due to bronchial compression from dilated pulmonary arteries and an enlarged right atrium. 7 In adults, respiratory symptoms caused by tracheobronchial compression are most commonly due to aortic aneurysms in the setting of atherosclerosis. 8 To our knowledge, there have been no reports of tracheobronchial compression in patients with idiopathic pulmonary arterial hypertension and pulmonary arterial dilatation. We present the first report of an adult patient with severe idiopathic pulmonary arterial hypertension and pulmonary arterial dilatation associated with symptomatic left main bronchus compression. In addition, we present a case of adult congenital heart disease associated with pulmonary arterial dilatation, with progressive, symptomatic bronchus intermedius and right middle lobe bronchus compression.
CASE DESCRIPTIONPatient A is a 73-year-old female who was diagnosed and commenced on treatment for idiopathic pulmonary arterial hypertension 11 years earlier. On diagnosis, she had a pulmonary arterial systolic pressure of 98 mmHg, diastolic pressure of 40 mmHg, mean pulmonary artery pressure of 67 mmHg, pulmonary capillary wedge pressure of 8 mmHg, mean right atrial pressure of 10 mmHg, cardiac index of 1.92 L/min/m 2 , and pulmonary vascular resistance of 1,181 dyn-s/cm 5 on right heart catheterization. She was noted to have enlarged pulmonary arteries, 1.5 times the size of the aorta on computed tomography (CT). Over time, she progressed from New York Heart Association (NYHA) class II to class IV symptoms.C...