Vasculite c-ANCA relacionada em paciente com retocolite ulcerativa: relato de caso*

Santos, Cristiane Engel dos; Pizzol, Vanessa Irusta Dal; Aragão, Salun Coelho; Filho, Acir Rachid; Marques, Fabrício Machado

doi:10.1590/s0482-50042013000500012

Cited by 5 publications

(8 citation statements)

References 7 publications

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“…Laboratory evidence of positive ANCA, in particular c-ANCA or PR3-ANCA, and a compatible kidney biopsy, are supportive findings of GPA diagnosis. Lung involvement of ulcerative colitis associated with ANCA positivity may also mimic GPA [71]. …”

Section: Lung Involvement In Childhood-onset Gpamentioning

confidence: 99%

Lung involvement in childhood onset granulomatosis with polyangiitis

et al. 2017

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Granulomatosis with polyangiitis is an ANCA-associated systemic vasculitis with a low incidence in the pediatric population. Lung involvement is a common manifestation in children affected by granulomatosis with polyangiitis, both at disease’s onset and during flares. Its severity is variable, ranging from asymptomatic pulmonary lesions to dramatic life-threatening clinical presentations such as diffuse alveolar haemorrhage. Several radiologic findings have been described, but the most frequent abnormalities detected are nodular lesions and fixed infiltrates. Interstitial involvement, pleural disease and pulmonary embolism are less common. Histology may show necrotizing or granulomatous vasculitis of small arteries and veins of the lung, but since typical features may be patchy, the site for lung biopsy should be carefully chosen with the help of imaging techniques such as computed tomography. Bronchoalveolar lavage is helpful to confirm the diagnosis of alveolar haemorrhage. Pulmonary function tests are frequently altered, showing a reduction in the diffusion capacity for carbon monoxide, which can be associated with obstructive abnormalities related to airway stenosis. Nodular lung lesions tend to regress with immunosuppressive therapy, but lung disease may also require second line treatments such as plasmapheresis. In cases of massive diffuse alveolar haemorrhage, ventilator support is crucial in the management of the patient.

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Section: Lung Involvement In Childhood-onset Gpamentioning

confidence: 99%

Lung involvement in childhood onset granulomatosis with polyangiitis

et al. 2017

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“…Em geral, o desenvolvimento de aplicação de RNA segue as seguintes etapas: 8 (1) obtenção de dados; (2) separação de conjuntos para treinamento e verificação; (3) configuração da rede; (4) treinamento; (5) verificação.…”

Section: Resultsunclassified

“…Garantir o acesso à água significa mais do que apenas atendimento a necessidades básicas, pois "a garantia do acesso à qualidade da água assegura acesso justo à saúde, desenvolvimento econômico e ambientes ecologicamente saudáveis para uma nação". 8 Desta forma, com o risco de redução da quantidade de água no futuro e a qualidade das águas disponíveis atualmente nos rios cada vez mais comprometida, torna-se estratégico entender o Oxigênio Dissolvido (OD), com vistas à preservação dos corpos hídricos, que vêm sofrendo com pressões do aumento populacional, uso por indústrias, localizadas nas regiões mais populosas, além da utilização para irrigação e produção de alimentos, responsável por grande uso e poluição dos recursos hídricos. Modelar este parâmetro é importante em função de seu próprio valor para os cursos de água superficiais.…”

Section: Introductionunclassified

Reduction of Input Variables in Artificial Neural Networks as From Principal Components Analysis Data in the Modeling of Dissolved Oxygen

Silva¹,

Schimidt²

2016

Química Nova

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“…Water pollution is a principal cause of health disorders worldwide. [1][2][3] Increasing industrial activity, especially in developing countries, often involves contamination of water with soluble toxic metal-ion pollutants that readily accumulate in humans and animals. 3,4 Exposure to heavy metals such as arsenic, cadmium, chromium, lead and mercury, even at trace levels, is especially pernicious to human health.…”

Section: Introductionmentioning

confidence: 99%

MOF-Beads Containing Inorganic Nanoparticles for the Simultaneous Removal of Multiple Heavy Metals from Water

Boix

Troyano

Garzón‐Tovar

et al. 2020

ACS Appl. Mater. Interfaces

111

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Pollution of water with heavy metals is a global environmental problem whose impact is especially severe in developing countries. Among water-purification methods, adsorption of heavy metals has proven to be simple, versatile and cost-effective. However, there is still a need to develop adsorbents with a capacity to remove multiple metal pollutants from the same water sample. Herein we report the complementary adsorption capacities of metal-organic frameworks (MOFs; here, UiO-66 and UiO-66(SH)2) and inorganic nanoparticles (iNPs; here, cerium-oxide NPs) into composite materials. These adsorbents, which are spherical microbeads generated in one step by continuous-flow spray-drying, efficiently and simultaneously remove multiple heavy metals from water, including As(III and V), Cd(II), Cr(III and VI), Cu(II), Pb(II) and Hg(II). We further show that these microbeads can be used as packing material in a prototype of a continuous-flow water treatment system, in which they retain their metal-removal capacities upon regeneration with a gentle acidic treatment. As proof-of-concept, we evaluated these adsorbents for purification of laboratory water samples prepared to independently recapitulate each of two strongly-polluted rivers: the Bone (Indonesia) and Buringanga (Bangladesh) rivers. In both cases, our microbeads reduced the levels of all the metal contaminants to below the corresponding permissible limits established by the World Health Organization (WHO). Moreover, we demonstrated the capacity of these microbeads to lower levels of Cr(VI) in a water sample collected from the Sarno River (Italy). Finally, to create adsorbents that could be magnetically recovered following their use in water purification, we extended our spraydrying technique to simultaneously incorporate two types of iNPs (CeO2 and Fe3O4) into UiO-66(SH)2, obtaining CeO2/Fe3O4@UiO-66-(SH)2 microbeads that adsorb heavy metals and are magnetically responsive.water by a magnet. Given their ready formation and tunability, we are confident that such iNP@MOF-Beads will prove utile in future water-purification applications.

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Vasculite c-ANCA relacionada em paciente com retocolite ulcerativa: relato de caso*

Cited by 5 publications

References 7 publications

Lung involvement in childhood onset granulomatosis with polyangiitis

Lung involvement in childhood onset granulomatosis with polyangiitis

Reduction of Input Variables in Artificial Neural Networks as From Principal Components Analysis Data in the Modeling of Dissolved Oxygen

MOF-Beads Containing Inorganic Nanoparticles for the Simultaneous Removal of Multiple Heavy Metals from Water

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