Vasculitis Presenting as Otitis Media

Jh, Per-Lee; Rc, Parsons

doi:10.1097/00007611-196902000-00007

Cited by 27 publications

(5 citation statements)

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“…Occasionally the otological manifestation may be the first and only sign of Wegener's Granulomatosis (McCaffrey et al, 1980;Per-Lee and Parsons, 1969;Blatt and Lawrence, 1961). This is a case report of Wegener's Granulomatosis in a young man who had bilateral otitis media associated with a facial palsy, followed by a discussion of the difficulties encountered in making the correct diagnosis.…”

Section: Introductionmentioning

confidence: 91%

Wegener's Granulomatosis of the ear

Bradley¹

1983

J. Laryngol. Otol.

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Section: Introductionmentioning

confidence: 91%

Wegener's Granulomatosis of the ear

Bradley¹

1983

J. Laryngol. Otol.

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“…It may be due to vasculitis of the cochlear vessels, granuloma pressing on the acoustic nerve, and deposition of immune complexes in the cochlea. Otological involvement with Wegener's granulomatosis has been reported by many authors, but they do not describe it either as the initial problem or subsequent to nasal involvement (Fahey et al, 1954;Blatt and Lawrence, 1961;Per-Lee and Parson, 1969;Novack and Pearson, 1971;Linthicum and Schwartzman, 1972;Bourdiniere et al, 1973;Friedmann and Bauer, 1973).…”

Section: Introductionmentioning

confidence: 99%

Cochlear implantation in a case of Wegener's granulomatosis

1996

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Cochlear implantation is now a routine clinical procedure for deaf patients in many countries (Gibson, 1987). It replaces the function of damaged cochlear hair cells and, therefore, detects sound and by electrical stimulation produces an appropriate signal in the remaining cochlear nerve fibres (House and Berliner, 1991). Wegener's granulomatosis is an uncommon auto-immune disease. It has a peak incidence at the fifth decade with slight male predominance. Nasal problems are the predominant presentation with otological manifestations presenting rarely. We report a case of Wegener's granulomatosis presenting with total hearing loss and after right cochlear implantation a free field threshold of 40 dB and 20 per cent Bamford-Kowal-Bench (BKB) speech test.We conclude that Wegener's granulomatosis is not an absolute contraindication for cochlear implantation.

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“…Ossification has also been described in the cochlea (Blatt and Lawrence, 1961) and the viscosity of the perilymph is increased by a rise in its protein content (Friedmann and Bauer, 1973). Sensorineural deafness may be caused by a vasculitis affecting the vasa nervorum of the VHIth nerve, the internal auditory artery or its cochlear branch (Drachman, 1963;Peitersen and Carlsen, 1965;Per-Lee and Parsons, 1969).…”

Section: Discussionmentioning

confidence: 99%

Recovery from sensorineural deafness in Wegener's granulomatosis

et al. 1989

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Wegener's granulomatosis may present with deafness or other aural symptoms. This report describes two patients with histological evidence of Wegener's granulomatosis who developed reversible sensorineural hearing loss during the course of their illness. The first patient showed complete recovery of a sensorineural hearing loss averaging 50 dB after ten months treatment with cyclophosphamide and high-dose prednisolone. The second patient, who was on maintenance haemodialysis, achieved a 40 dB improvement in sensorineural hearing loss within two weeks of adding cyclophosphamide to pre-existing corticosteroid therapy. These findings suggest that the prognosis of sensorineural hearing loss in Wegener's granulomatosis can be improved with suppression of the vasculitic process by early treatment with combined cytotoxic-immunosuppressive therapy

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Vasculitis Presenting as Otitis Media

Cited by 27 publications

References 0 publications

Wegener's Granulomatosis of the ear

Wegener's Granulomatosis of the ear

Cochlear implantation in a case of Wegener's granulomatosis

Recovery from sensorineural deafness in Wegener's granulomatosis

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