Vasomotion analysis of speed resolved perfusion, oxygen saturation, red blood cell tissue fraction, and vessel diameter: Novel microvascular perspectives

Fredriksson, Ingemar; Larsson, Marcus; Strömberg, Tomas; Iredahl, Fredrik

doi:10.1111/srt.13106

Cited by 15 publications

(9 citation statements)

References 49 publications

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“…: emergency team, emergency theatre, etc.). Our findings confirm considerations about the importance of the vasomotion wave 15,19 . At present, our policy is to promptly re-explore free flaps whose monitoring shows fading of vasomotion.…”

Section: Discussionsupporting

confidence: 87%

Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery

Salvatori¹,

Paradisi

Zani³

2022

Acta Otorhinolaryngol Ital

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Objective. Early recognition of free flap vascular impairment is essential for flap salvage attempts. Several methods for surveillance of post-operative flaps are available. Among these, we have extensively used Laser-Doppler Perfusion Flowmetry (LDF) monitoring. We report our experience on this topic and illustrate the advantages and weak points. Methods. Over seven years, 110 consecutive free flaps for head and neck reconstruction were monitored using the Periflux System 5000 ® (Perimed AB, Järfälla, Sweden). In addition to maximum and minimum peaks, a pattern called vasomotion can be detected. Monitoring time lasted from 3 to 7 days, 24/24 h. Results. Six of 110 (5.5%) cases of vascular problems were detected and clinically confirmed. In 5 cases, venous thrombosis was present: 4 patients were successfully treated. In 1 case, both arterial and venous thrombosis occurred. Flowmetry data always showed a more or less sudden disappearance of vasomotion. Conclusions. LDF is a highly sensible, specific and reliable method. It is easy to use and interpret at low cost. Remote monitoring could also be developed.

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Section: Discussionsupporting

confidence: 87%

Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery

Salvatori¹,

Paradisi

Zani³

2022

Acta Otorhinolaryngol Ital

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“…Diabetic patients were found to have endothelial dysfunction in some arteries ( De Ciuceis, 2020 ). Detecting microvascular dysfunction before diabetic complications could play an important role in the pre-diagnosis of diabetes ( Fredriksson et al, 2021 ). There is physiological significance to provide insight into different microvascular impacts.…”

Section: Introductionmentioning

confidence: 99%

The Origin of Vasomotion and Stochastic Resonance in Vasomotion

Liu

ZHAO

Liu

2022

Front. Bioeng. Biotechnol.

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Vasomotion is the spontaneous time-dependent contraction and relaxation of micro arteries and the oscillating frequency is about 0.01–0.1 Hz. The physiological mechanism of vasomotion has not been thoroughly understood. From the dynamics point of view, the heartbeat is the only external loading exerted on the vascular system. We speculate that the nonlinear vascular system and the variable period of the heartbeat might induce the low-frequency vasomotion. In this study, the laser Doppler flowmeter is used to measure the time series of radial artery blood flow and reconstructed modified time series that has the same period as the measured time series but different heartbeat curves. We measured the time series of radial artery blood flow in different conditions by adding different noise disturbances on the forearm, and we decomposed the experiment pulse signal by Hilbert–Huang transform. The wavelet spectral analyses showed that the low-frequency components were induced by the variable period but independent of the shape of the heartbeat curve. Furthermore, we simulated the linear flow in a single pipe and the nonlinear flow in a piping network and found that the nonlinear flow would generate low-frequency components. From the results, we could deduce that the variable period of heartbeat and the nonlinearity of the vascular system induce vasomotion. The noise has effects on the blood signals related to the respiratory activities (∼0.3 Hz) but little influence on that related to the cardiac activities (∼1 Hz). Adding white noise and then stopping would induce an SNR increase in the frequency band related to vasomotion (∼0.1 Hz).

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“…The separation into speed-resolved perfusion might also enable new tests, by performing the frequency analysis on the individual speed components, loosely representing different vasculatures. This was recently demonstrated in speedresolved LDF [107].…”

Section: Clinical Potentialmentioning

confidence: 60%

Real-time multi-exposure laser speckle contrast imaging of skin microcirculatory perfusion

Hultman

2022

Linköping Studies in Science and Technology. Dissertations

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Vasomotion analysis of speed resolved perfusion, oxygen saturation, red blood cell tissue fraction, and vessel diameter: Novel microvascular perspectives

Cited by 15 publications

References 49 publications

Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery

Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery

The Origin of Vasomotion and Stochastic Resonance in Vasomotion

Real-time multi-exposure laser speckle contrast imaging of skin microcirculatory perfusion

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