Vasopressin and epinephrine in the treatment of cardiac arrest: an experimental study

Abstract

Background Epinephrine remains the drug of choice for cardiopulmonary resuscitation. The aim of the present study is to assess whether the combination of vasopressin and epinephrine, given their different mechanisms of action, provides better results than epinephrine alone in cardiopulmonary resuscitation.

RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 4: Advanced life support

“…Stadlbauer et al (LOE 6, fair/supporting) showed similar results when vasopressin was used in combination with epinephrine . Stroumpoulis et al (LOE 6, good/supporting) found improved ROSC and CPPs in a piglet VF model when vasopressin was used in combination with epinephrine compared to epinephrine alone . Two porcine models, one (LOE 6, fair/neutral) and one (LOE 6, good/neutral) demonstrated improvement in hemodynamic parameters, such as CPP, but found no improvement in ROSC or neurological outcome with the use vasopressin.…”

Swine model in cardiopulmonary resuscitation research

“…Επομένως, γίνεται κατανοη τό ότι η ελάχιστη αιμοδυναμική παρακολούθηση σε έ να τέτοιο μοντέλο πειραματισμού είναι μια αιματηρή πίεση της Αορτής και μια αιματηρή πίεση στο δεξιό κόλπο (Xanthos et al 2007a). Επομένως, απαιτείται η προώθηση ενός αρτηριακού καθετήρα στη θωρακική αορτή είτε μέσω της καρωτίδας (Stroumpoulis et al 2008) είτε μέσω της μηριαίας αρτηρίας, καθώς και η προώθηση ενός καθετήρα στο δεξιό κόλπο μέσω της έσω σφαγίτιδας φλέβας (Bassiakou et al 2008). Στη συνέχεια, οι καθετήρες αυτοί συνδέονται μέσω κα τάλληλων μορφομετατροπέων σε monitor ικανό να καταγράφει τιμές και κυματομορφές των μετρουμέ νων πιέσεων.…”

Fluorescence Sensing Platforms for Epinephrine Detection Based on Low Temperature Cofired Ceramics

“…Additionally, this catecholamine shows a number of hormonal actions, for instance, it is involved in a wide range of metabolic processes, such as gastrointestinal (GI) physiology-it affects gut motility, nutrient absorption, GI innate immune system and the microbiome [4]. EP in medical treatment is used as an agent during resuscitation, after a heart attack and for bronchial asthma attacks, because it stimulates beta receptors leading to vasodilation at low doses (which would increase blood flow) and vasoconstriction at high doses [4][5][6]. Because of its importance, it is crucial to develop a new, cost-effective and simple method for sensitive and selective EP determination.…”