“…However, the quantity of flow in the Hole-ICL was large in a channel running through the hole in the centre, because the distance between the iris and the ICL was narrow. Therefore, the circulation of aqueous humour to the anterior surface of the Several causes of secondary cataracts in patients with conventional ICL have been postulated, including aqueous humour circulation [5,6], pIOL-crystalline lens contact [7,8], low vaulting between the ICL and the crystalline lens [9][10][11], the decreased anterior chamber depth occurring with age [12], myopia [13], and surgical trauma [14]. In particular, Fujisawa et al [5] and Shiratani et al [6] performed histopathological studies that revealed the importance of aqueous humour circulation in the vault between the ICL and the crystalline lens in preventing secondary cataracts.…”