In the Agriculture sector, the farmers need a reliable estimation for pre-harvest crop yield prediction to decide their import-export policies. The present work aims to assess the impact of remote sensing-based derived products with Climate data on the accuracy of a prediction model for the sugarcane yield. The regression method was used to develop an empirical model based on VCI, Historical Sugarcane Yield, and Climatic Parameters of 75 districts of six major sugar-producing states of India. The MOD13Q1 product of MODIS on Board Terra Satellite at 16-day intervals was accessed during the growing season of sugarcane crop with 36 meteorological parameters for experimentation. The accuracy of the model was evaluated using R 2 , Root Mean square Metric (RMSE), Mean Absolute Error (MAE), and mean square error (MSE). The preliminary results concluded that the proposed methodology achieved the highest accuracy with (R 2 =0.95, MAE=5.18, MSE=34.5, RMSE=5.87). The conclusion of the study highlighted that the coefficient of determination can be improved significantly by incorporating maximum and minimum temperature parameters with Remote sensing derived vegetation indices for the sugarcane yield.