The Lake Baikal region of southern Siberia has a rich mortuary record with good skeletal preservation that has provided the most comprehensive isotopic database for palaeodietary studies of north-temperate hunter-gatherers in the world. Building on previous work, this study contributes new δ C, δ N, and AMS radiocarbon dating results from the cemeteries of Verkholensk (n = 44) in the Upper Lena River micro-region and Ulan-Khada (n = 19) in the Little Sea micro-region. Our results reveal several previously unrecognized patterns. Early Bronze Age (EBA, 4600-3700 cal BP) individuals at Verkholensk exhibit lower δ 15 N values than in the Late Neolithic (LN, 5570-4600 cal BP), suggesting a shift to a more terrestrial diet in the later period. In addition, EBA individuals at Verkholensk differ in both δ 13 C and δ 15 N from those at the nearby site of Obkhoi, suggesting territorial divisions at a surprisingly small scale, though there is a diachronic component that also needs to be considered. The comparison highlights the need for additional work on freshwater reservoir corrections for the Upper Lena. The Ulan-Khada EBA results are consistent with the dietary patterns previously identified for the Little Sea micro-region, with a division into distinct 'Game-Fish' and 'Game-Fish-Seal' diets. A new finding is that EBA females with Game-Fish-Seal diets for the whole of the Little Sea sample display significantly lower mean δ 13 C values than their male counterparts.A small number of outliers in δ 13 C and/or δ 15 N were identified at both Verkholensk and Ulan-Khada that may support previous suggestions of migration between the Upper Lena and Little Sea micro-regions. Exploratory use of δ 18 O isotopes in bone collagen offers a novel line of support for this scenario, but further research is needed.