Creating a safe and comfortable environment, developing a human, is a priority of urban development. One of the important stages of the solution to such a problem is the actualization of the regulatory base in the field of city-building, which should lay the principles of a city, developing a human and promoting better health. The work shows the feasibility for quantitative analysis of safety and comfortable spatial environment when creating general plans of cities and their territorial entities. So, using the method of calculating the integral index of spatial-temporal accessibility of objects that implement the functions of the city, we suggest performing a comprehensive quantitative evaluation of planning decisions in terms of placing of socially significant objects. A key prerequisite for the calculation of this index was the inclusion of the time parameter provided to a person to realize his/her rational needs. This approach is based on the principles of creating biosphere compatible cities that develop a person, and allows not only more fully appreciate the quality of urban planning decisions, but also to consider the interests of groups with different mobility. As an example, we determined the level of implementation of the city functions "Knowledge" (components-preschool and general education) and "Entertainment and leisure" (componentrecreation open urban green spaces) for different groups in a new microdistrict in Orel. The calculation of the indicator was carried out for children aged 3-4 years, 7-8 years, healthy young people, people in old age and residents with disorders of the musculoskeletal system. For the latter, the obtained values differ from the maximum possible. The analysis noted the insufficient capacity of educational institutions, reflecting a defective personal availability.