To investigate the effects of muscle fatigue on bioinspired robot learning quality in teaching by demonstration (TbD) tasks, in this work, we propose to first identify the emerging muscle fatigue phenomenon of the human demonstrator by analyzing his/her surface Electromyography (sEMG) recordings and then guide the robot learning curve with this knowledge in mind. The time-varying amplitude and frequency sequences determining the subband sEMG signals have been estimated and their dominant values over short time intervals have been explored as fatigue-indicating features. These features are found carrying muscle fatigue cues of the human demonstrator in the course of robot manipulation. In robot learning tasks requiring multiple demonstrations, the fatiguing status of human demonstrator can be acquired by tracking the changes of the proposed features over time. In order to model data from multiple demonstrations, Gaussian mixture models (GMMs) have been employed. According to the identified muscle fatigue factor, a weight has been assigned to each of the demonstration trials in training stage, which is therefore termed as weighted GMMs (W-GMMs) algorithm. Six groups of data with various fatiguing status, as well as their corresponding weights, are taken as input data to get the adapted W-GMMs parameters. After that, Gaussian mixture regression (GMR) algorithm has been applied to regenerate the movement trajectory for the robot. TbD experiments on Baxter robot with 30 human demonstration trials show that the robot can successfully accomplish the taught task with a generated trajectory much closer to that of the desirable condition where little fatigue exists.