Ven�se Beimischung und Lungenkreislauf bei Lebercirrhose

Schwab, Max; Schröder, Rolf; Dissmann, T; Dissmann, W; Heimburg, P; Hüttemann, U.; Schüren, K. P.

doi:10.1007/bf01490015

Cited by 22 publications

(5 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cyanosis and clubbing may occur as a result of pulmonary arterial venous fistulae and shunts between the portal and pulmonary circulation (11,27,(32)(33)(34)(35).…”

Section: Discussionmentioning

confidence: 99%

Ventricular function in cirrhosis and portasystemic shunt: A two-dimensional echocardiographic study

et al. 1988

View full text Add to dashboard Cite

Cardiovascular alterations such as increased heart rate, high cardiac output, reduced systemic vascular resistance, and in most of the cases, increased contractility parameters have been recognized in patients with advanced liver disease. Some investigators define a cirrhotic cardiomyopathy as a hyperdynamic failure of the heart. Consequently, in patients with cirrhosis, the risk of developing further circulatory deterioration may be increased in situations which stress the cardiovascular system. After opening a portocaval shunt, it is expected that a large amount of blood will be distributed from the splanchnic to the pulmonary circulation and put a strain on the heart. This two-dimensional echocardiographic study was made in 30 patients with cirrhosis and in 20 patients who were chronically treated (range: 16 to 156 months) with portasystemic shunt for prevention of hemorrhage from esophageal variceal bleeding. Patients with portasystemic shunts revealed a change in hemodynamic pattern. There was a significant increase in the left ventricular end-diastolic volume index and also a slight increase in the left ventricular end-systolic index. Cardiac output remained high despite a significant decrease in heart rate due to an elevated left ventricular stroke volume index. The parameters of systolic ventricular performance were normal. In contrast to the acute opening of the portacaval shunt, the chronic shunt volume put no strain of clinical significance on the heart.

show abstract

“…Cyanosis and clubbing may occur as a result of pulmonary arterial venous fistulae and shunts between the portal and pulmonary circulation (11,27,(32)(33)(34)(35).…”

Section: Discussionmentioning

confidence: 99%

Ventricular function in cirrhosis and portasystemic shunt: A two-dimensional echocardiographic study

et al. 1988

View full text Add to dashboard Cite

show abstract

“…The following results were obtained: (1) there was no inequality of ventilation as judged by a nitrogen washout study; (2) a large true venous admixture was found in all patients; (3) in four patients studied twice venous admixture was larger when mean EEG frequency was lower; (4) besides the true venous admixture a low overall D/Q ratio was an important factor contributing to un saturation in most cases; (5) in some cases a decreased overall V/Q ratio contributed to the unsaturation. This decreased V/Q ratio appeared to be due to an increase in pulmonary perfusion without a concomitant rise in ventilation.Changes in pulmonary perfusion pathways are suggested as the most likely cause of the defect in oxygen transfer found in patients with cirrhosis.Patients with chronic liver disease may show arterial hypoxemia and an increased alveolar-arterial O2 gradient (AaDOa), which by the majority of authors is attributed to increased venous admixture [7,23,33,34]. Results of previous studies suggested that the extent of venous admixture in indivi dual patients is not constant but varies widely during the course of the disea se.…”

mentioning

confidence: 97%

Pulmonary Function Studies and Oxygen Transfer in Patients with Liver Cirrhosis and Different Degree of Portasystemic Encephalopathy

Schomerus¹,

Buchta²,

Arndt³

1975

Respiration

View full text Add to dashboard Cite

Pulmonary function and oxygen transfer was studied in five patients with cirrhosis of the liver and different degrees of portasystemic encephalopathy. Four patients were restudied after a change in CNS function. The contribution of various parameters of pulmonary gas exchange to the unsaturation found was evaluated employing the graphic analysis described by King and Briscoe. The following results were obtained: (1) there was no inequality of ventilation as judged by a nitrogen washout study; (2) a large true venous admixture was found in all patients; (3) in four patients studied twice venous admixture was larger when mean EEG frequency was lower; (4) besides the true venous admixture a low overall D/Q ratio was an important factor contributing to unsaturation in most cases; (5) in some cases a decreased overall V/Q ratio contributed to the unsaturation. This decreased V/Q ratio appeared to be due to an increase in pulmonary perfusion without a concomitant rise in ventilation. Changes in pulmonary perfusion pathways are suggested as the most likely cause of the defect in oxygen transfer found in patients with cirrhosis.

show abstract

“…D ie g efu n d e n e n W e rte stim m e n m it d e n A n g ab en des S c h rifttu m s g u t ü b e re in : B artels [22]; U lmer u n d R eichel [23]; L oew u n d T hew s [24]; Schwab et al [13]. L ediglich d e r a rte rie lle 0 2-D ru c k lieg t b e i P a tie n te n m it L u n g e n tu m o re n niedriger.…”

Section: Ergebnisseunclassified

“…L ediglich d e r a rte rie lle 0 2-D ru c k lieg t b e i P a tie n te n m it L u n g e n tu m o re n niedriger. [13] …”

Section: Ergebnisseunclassified

Zur Deutung perfusionsszintigraphischer Befunde bei malignen Lungentumoren

Kunkel¹,

Hüttemann²,

Ernst³

et al. 1968

Respiration

View full text Add to dashboard Cite

Ven�se Beimischung und Lungenkreislauf bei Lebercirrhose

Cited by 22 publications

References 57 publications

Ventricular function in cirrhosis and portasystemic shunt: A two-dimensional echocardiographic study

Ventricular function in cirrhosis and portasystemic shunt: A two-dimensional echocardiographic study

Pulmonary Function Studies and Oxygen Transfer in Patients with Liver Cirrhosis and Different Degree of Portasystemic Encephalopathy

Zur Deutung perfusionsszintigraphischer Befunde bei malignen Lungentumoren

Contact Info

Product

Resources

About