Venom-derived peptides for breaking through the glass ceiling of drug development
Lou Freuville,
Chloé Matthys,
Loïc Quinton
et al.
Abstract:Venoms are complex mixtures produced by animals and consist of hundreds of components including small molecules, peptides, and enzymes selected for effectiveness and efficacy over millions of years of evolution. With the development of venomics, which combines genomics, transcriptomics, and proteomics to study animal venoms and their effects deeply, researchers have identified molecules that selectively and effectively act against membrane targets, such as ion channels and G protein-coupled receptors. Due to t… Show more
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