Venous and Skin puncture blood counts compared

Bellamy, G J; Hinchliffe, R F

doi:10.1111/j.1365-2257.1988.tb00026.x

Cited by 12 publications

(6 citation statements)

References 11 publications

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“…A number of factors may contribute to the differences between the findings of the present and earlier reports, including the number and race of the children studied, the methods employed, and the type of sample used. For example, Cranendonk et al (1985) used capillary blood which gives leucocyte values some 3–12% higher than those found in paired venous samples ( Bellamy & Hinchliffe 1988; Cracknell, Hinchliffe & Lilleyman 1995). This may contribute to, but cannot entirely explain, the differences in the lower limits of the leucocyte and neutrophil values between the two studies.…”

Section: Discussionmentioning

confidence: 99%

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

Bellamy¹,

Hinchliffe²,

Crawshaw³

et al. 2000

Clinical &Amp; Laboratory Haematology

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Reference ranges for the total and differential leucocyte counts were determined from venous blood collected at 2, 5 and 13 months of age from a cohort of 112 healthy children of north European ancestry. At 2, 5 and 13 months, the ranges for neutrophils were found to be 0.7-4.7, 1.1-5.6 and 1.0-7.6 x 109/l, and for lymphocytes 3.3-10.5, 3.4-11.3 and 3.5-10.4 x 109/l, respectively. The upper limits for monocytes at each age were 1.2, 1.2 and 0.91 x 109/l, and for eosinophils 0.84, 1.0 and 0.88 x 109/l, respectively. Mean counts for all cell types, except monocytes, increased between 2 and 5 months of age. There was little change in mean counts between 5 and 13 months. Statistically significant correlations existed between the numbers of each cell type at 2 months of age, and were still present at 13 months between monocytes and each of the granulocyte series and between basophils and all other cell types. By comparison with older data these findings indicate a lower reference limit for neutrophils at 2 months of age, and a narrower range for this cell type at both 2 and 5 months of age. Reference ranges for lymphocytes and eosinophils are wider than indicated by some previous studies.

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Section: Discussionmentioning

confidence: 99%

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

Bellamy¹,

Hinchliffe²,

Crawshaw³

et al. 2000

Clinical &Amp; Laboratory Haematology

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“…Several studies have shown that the capillary WBC is higher than the venous WBC in adults [35], children [36,37] and neonates [38]. In addition, the venous blood was diluted with anticoagulant, which could also account for the lower number of leukocytes in venous blood Table 4 The Spearman correlation coefficient between aggregation parameters in capillary and venous blood and the acute phase reactants.…”

Section: Discussionmentioning

confidence: 99%

Capillary and Venous Leukocyte Adhesiveness/Aggregation to Differentiate between Viral and Bacterial Infection

Rotstein¹,

Kassirer²,

Zeltser³

et al. 2002

Infection

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“…The largest discrepancies in Hb concentrations between venous and capillary were reported in the neonatal period and specifically in acutely ill children, with the Hemocue producing lower values than the laboratory analysers. The highest difference between the two sample types was seen in anaemic children [8,9,16,18,19].…”

Section: Venous Versus Capillary Blood Samplesmentioning

confidence: 91%

Hemocue Validation for the Diagnosis of Anaemia in Children: A Semi- Systematic Review

M¹

2014

Pediat Therapeut

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Background: Numerous methods are endorsed for Haemoglobin (Hb) estimation and anaemia assessment. The Hemocue is being introduced for routine use in clinics and hospitals in many developing nations. There are a number of illustrative cases that establish a clinical connection readily, but these have mainly been with adults. This study seeks tore view literature on the diagnostic accuracy of the Hemocue among children. Methodology: This is a semi-systematic review of studies analysing the Hemocue device's diagnostic accuracy determining haemoglobin levels among children aged zero to fifteen years. Results: 18 studies were included. The main finding of this investigation is that the Hemocue system is a good screening test, being sensitive and reliably projecting necessity of a full blood count. It is not likely that diagnosis of a clinically significant condition can be overlooked by this investigation. Thus it would seem to be a useful method to use for Hb screening in appropriate situations. The studies reviewed generally reported a difference between the means obtained by Hemocue Laboratory analyser, though these did not reach statistical significance. A trend for underestimation of Hb values was reported with most studies. The Hemocue had a sensitivity range of 75-91%, specificity range of 88-100% and positive predictive values ranging from 75-80% for the detection of anaemia. The mean difference in Hb from paired samples ranged from 0.2-0.35 g/dl (0.7%). Conclusion: The Hemocue is comparable to usual laboratory methods for determination of Hb level in children. It is well appropriate for use in care of healthy paediatric patients and children with hematologic disorders. A full blood count is recommended when anaemia is identified or in suspected non-anaemic iron deficiency.

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Venous and Skin puncture blood counts compared

Cited by 12 publications

References 11 publications

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

Capillary and Venous Leukocyte Adhesiveness/Aggregation to Differentiate between Viral and Bacterial Infection

Hemocue Validation for the Diagnosis of Anaemia in Children: A Semi- Systematic Review

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