Venous Gangrene

Phlegmasia caerulea dolens and venous gangrene are rare conditions that tend to occur in association with malignancy. They are characterized by total or near-total occlusion of the venous drainage of the limb, including the microvascular collaterals. Associated mortality and morbidity rates are high, especially when progression to venous gangrene has occurred. Treatment options are limited; elevation and anticoagulation are recommended as first-line management. Experience with thrombolysis has been disappointing although intra-arterial administration of thrombolytic agents may improve results. Thrombectomy cannot be advocated routinely. Little advance in management, or in life and limb salvage, has been made in the past 30 years.

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Phlegmasia caerulea dolens and venous gangrene

Perkins

Magee

Galland

1996

Journal of British Surgery

138

146

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Ischemic venous thrombosis caused by a distinct disturbance of the extrinsic clotting system

Duschet¹,

Seifert²,

Halbmayer

et al. 1993

Journal of the American Academy of Dermatology

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Ischemic venous thrombosis: Its hidden agenda

Anderson¹

1999

Journal of Vascular Nursing

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Venous Gangrene

Cited by 5 publications

References 13 publications

Phlegmasia caerulea dolens and venous gangrene

Phlegmasia caerulea dolens and venous gangrene

Ischemic venous thrombosis caused by a distinct disturbance of the extrinsic clotting system

Ischemic venous thrombosis: Its hidden agenda

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