Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Saad, Sameh

doi:10.5505/tjtes.2015.96832

Cited by 17 publications

(21 citation statements)

References 13 publications

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“…13 Random blood sugar measurement in polytrauma patient was missed in most of studies or had low application percentage .Although, It is have a high importance in prognosis and easy rapid biochemical predictors of mortality in patients with polytrauma. 14 Our study showed that that pelvic stability assessed in (65%) of cases which agree with Spanjersberg et al in which pelvic stability assessed in (64.8%) and Tsang et al, (65.6%). 9,11 And about 2 years survey, our study showed that for majority of cases head to toe examination was done percentage (78.6%), while AMPLE history was taken in minority of cases percentage (33%) ( Table 6).…”

Section: Discussionsupporting

confidence: 90%

Assessment of management of polytrauma patients in the emergency department in Suez Canal University hospital

et al. 2019

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Egypt is higher several times due to under-reporting and misclassification. 1 The Egyptian Ministry of Health estimated that 24,222 deaths, 127,216 hospitalizations and 847,912 disability-adjusted life years occurred due to ABSTRACT Background: Trauma is a serious global health problem, it is the fifth leading cause of significant disability and is still the most frequent cause of death in the first four decades of life, accounting for approximately one in 10 deaths worldwide. Methods: This study is cross sectional prospective study was conducted to evaluate assessment of management of patients according to the advanced trauma life support guideline in Emergency Department at Suez Canal University Hospital. All patients (n=103) were subjected to baseline assessment by history, clinical examination and investigations. The patients were followed up and recorded till the full assessment was done and the decision was made and the fate of the patient was recorded. Results: The majority of the studied patient had motor car crash (55.30%), while motor cycle crash was the second mechanism of trauma (21.40%), run over was the third mechanism (14.60%). Airway management was done (95.1%), cervical spine kept immobilized only in (71.8%). Blood pressure was measured in (97.1%) and 2ry survey assessment, head to toe examination (78.6%), while AMPLE history was taken in minority of cases percentage (33%). Finally majority of patients was admitted in ICU (44.70%), followed by 18.40% of the studied patient died and less than (2%) discharged from the ER. Conclusions: ATLS protocols provide a common framework and organized approach during polytrauma patient's management. Also, it has been shown to improve outcomes so we should enhance its application in our hospital.

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Section: Discussionsupporting

confidence: 90%

Assessment of management of polytrauma patients in the emergency department in Suez Canal University hospital

et al. 2019

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“…The main strength of this study are the strict matching criteria which all are proven and validated predictors of outcome in trauma (20,(30)(31)(32)(33).…”

Section: Strengths/limitationsmentioning

confidence: 99%

“…Furthermore, some of the matching criteria require critical discussion. Even though GCS, coagulopathy, BE and ISS are considered to be strong predictors for adverse outcome in trauma (29), elderly patients are presenting with more comorbidities, hence there might be a bias within the matching itself due to pre-existing conditions (20,(30)(31)(32)(33). It is more likely to nd a pre-existing decreased GCS in an older patient.…”

Section: Mortalitymentioning

confidence: 99%

Is there any difference in the outcome of geriatric and non-geriatric severely injured patients? – A seven-year, retrospective, observational cohort study with matched-pair analysis

Jensen¹,

Lempert²,

Sprengel³

et al. 2020

Preprint

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Background: The aging population has a tremendous impact on health care. Geriatric trauma is expected to increase due to the lifestyle and activity of the aging population and will be one of the major future challenges in health care. Therefore, the aim of this study was to investigate differences between polytraumatized geriatric and non-geriatric patients regarding 1) mortality, 2) length of stay, and 3) complications with a matched pair analysis. Methods: We included patients older than 17 years with an Injury Severity Score (ISS) of 16 or more admitted to our level 1 trauma center between January 2008 and December 2015. The cohort was stratified into two groups (age < 70 years “non-geriatric”, age ≥ 70 years “geriatric”). One-to-one matching was performed based on gender, ISS, mechanism of injury (penetrating/blunt), Glasgow Coma Scale (GCS), base excess, and the presence of coagulopathy (INR ≥ 1.4). Outcome was compared using the paired t-test and McNemar-test. Results: A total of 1457 patients with a mean age of 62 (± 21) years were identified. There were 1022 male (72%) and 435 female patients. Three hundred forty six patients (24%) were older than 70 years. Matching resulted in 57 pairs. 1) Mortality (25% vs 32% respectively; p = 0.219) as well as 2) length of stay (12.5 (± 13.3) days vs 11.8 (± 11.8) days respectively, p = 0.754) were comparable between geriatric and non-geriatric polytraumatized patients. 3) The complication rate (34% vs. 56%, p = 0.031) was significantly higher in geriatric patients. Conclusion: Despite significantly higher complication rates amongst the geriatric trauma patients, there were no significant differences regarding mortality and length of stay in this matched pair analysis – indicating the possibility of similar outcome in geriatric polytraumatized patients receiving optimal care.

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“…In the <40 age group, its incidence is 44.9% and it is the most common cause of death. Th e mortality and morbidity rates and functional recovery are directly aff ected by professional and timely care 2,3 . Appropriate triage and optimization of treatment approach in such patients is one of the key factors that aff ect fi nal outcome in these patients 1,6,7 .…”

Section: Discussionmentioning

confidence: 99%

“…Patients with polytrauma are one of the greatest challenges faced by physicians 1 . Polytrauma is a term describing patients with multiple injuries that involve several parts of the body and compromise function of the body and/or organ involved [1][2][3] . Th e most popular and most commonly used defi nition of trauma is based on the Injury Severity Score (ISS) 2,4,5 .…”

Section: Introductionmentioning

confidence: 99%

Erythropoietin in the Evaluation of Treatment Outcomes in Patients with Polytrauma

Arsenijević

Šijački

Marjanović

et al. 2017

ACC

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Polytrauma is a term describing patients with injuries involving multiple body regions that compromises function of the body and/or organ involved. The aim of the study was to evaluate the potential role of erythropoietin in predicting poorer outcome in trauma patients. This prospective study included 86 patients admitted to the Emergency Center of Serbia due to polytrauma assigned according to Injury Severity Score (ISS). The patients were further evaluated using the Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores and erythropoietin levels. There was a significant difference among erythropoietin levels at admission, after 48 and 72 hours, and on day 7 of hospital stay, with significantly higher levels in patients with ISS values 49-75. Based on the results, ROC curves were used to identify cut-off levels to predict ISS score with critical clinical course. It was concluded that erythropoietin could be a good marker of injury severity. Further research has to be performed to determine the cut-off values of erythropoietin that are significant for injury severity.

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Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Cited by 17 publications

References 13 publications

Assessment of management of polytrauma patients in the emergency department in Suez Canal University hospital

Assessment of management of polytrauma patients in the emergency department in Suez Canal University hospital

Is there any difference in the outcome of geriatric and non-geriatric severely injured patients? – A seven-year, retrospective, observational cohort study with matched-pair analysis

Erythropoietin in the Evaluation of Treatment Outcomes in Patients with Polytrauma

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