Varfarina previne obstruções venosas pós-implante de dispositivos cardíacos em pacientes de alto risco: análise parcialWarfarin prevents venous obstruction after cardiac devices implantation in high-risk patients: partial analysis Abstract Introduction: The incidence of venous thrombosis after cardiac devices implantation is high. Ventricular dysfunction and previous transvenous temporary leads ipsilaterally to the permanent implantation are independent risk factors. The effect of prophylactic strategies to prevent these complications remains controversial.Objectives: To evaluate the efficacy of prophylactic use of warfarin in patients with high risk of lead-associated thrombosis.Method: Clinical, prospective, randomized and blinded study, in patients submitted to first transvenous leads implantation with LVEF < 0.40 and/or previous ipsilateral temporary pacing. After device implantation, patients were randomly assigned to placebo or warfarin. Periodical clinical and laboratorial evaluations were performed to anticoagulant management. After a six-month period, every patient was submitted to a digital subtraction venography.Results
543SILVA, KR ET AL -Warfarin prevents venous obstruction after cardiac devices implantation in high-risk patients: partial analysis Bras Cir Cardiovasc 2008; 23(4): 542-549
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