Venous Thromboembolic Complications of Lung Transplantation: A Contemporary Single-Institution Review

Abstract

The incidence of DVT and PE in lung transplant recipients is high. Posttransplant surveillance and treatment based on findings are warranted.

Prophylaxis with enoxaparin for prevention of venous thromboembolism after lung transplantation: a retrospective study

“…The 15% incidence of VTE in our cohort is similar to that reported for LT recipients in the literature, namely 8–29% . The single case of atrial thrombosis in 333 LT patients we recorded is within the expected range; we interpreted this problem as being directly related to the surgical procedure.…”

“…Our results show that VTE is a relevant complication following LT, mainly in the early postoperative period and that 90-day extended prophylaxis seems unable to prevent it. The 15% incidence of VTE in our cohort is similar to that reported for LT recipients in the literature, namely 8-29% [8][9][10][11]13,25,26]. The single case of atrial thrombosis in 333 LT patients we recorded is within the expected range; we interpreted this problem as being directly related to the surgical procedure.…”

“…Nevertheless, VTE seems to be more frequent in frail patients and therefore is associated with poorer prognosis. Following this line of argument, Evans et al [26] described DVT as a risk factor for patient survival (HR 2.43; 95% CI, 1.29-4.64), and Lingaraju et al [15] found VTE to be associated with poorer survival 3 months after LT.…”

Early postoperative management after lung transplantation: Results of an international survey

“…Lung transplantation is frequently complicated by VTE with a reported incidence of 8%‐45% . There are a number of traditional risk factors responsible for the increased incidence of VTE post‐transplantation including stasis, indwelling catheters, and a postoperative state.…”

Commentary: Deep venous thrombosis in lung transplant recipients—tip of the iceberg that can potentially affect long-term outcome?

“…As early as 1995, Kroshus and colleagues 4 in Dr Bolman's group in Minnesota published, in this very Journal, their concerns about this problem after lung and heart-lung transplantations. Other investigators have also subsequently reviewed the incidence and complications of venous thromboembolic events in the lung transplant population [5][6][7] and suggested that routine screening or surveillance is warranted. However, none of them has actually published a study that officially implemented a routine DVT screening protocol.…”