Venous thromboembolism prophylaxis in acutely ill medical patients: definite need for improvement

Chopard, Pierre; Dörffler‐Melly, Janine; Hess, U.; Wuillemin, Walter A.; Hayoz, Daniel; Gallino, Augusto; Bächli, Esther; Canova, Cristina; Isenegger, Jörg; Rubino, Rosa; Bounameaux, Henri

doi:10.1111/j.1365-2796.2005.01455.x

Cited by 83 publications

(92 citation statements)

References 16 publications

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“…20 At Hospital Geral de Roraima, 31.1% of physicians reported knowing DVT incidence in our country. In our study and in others, such as those by Marchi et al, 21 Caiafa & Bastos, 16 Rocha et al 22 and Deheinzelin et al, 23 all performed in Brazil, and those by Vallano et al 24 and Chopard et al, 25 performed in other countries, we can observe that most physicians do not submit patients with identified risk of DVT to prophylaxis (Table 10). According to Arnold et al, inadequate prophylaxis is more frequently caused by omission, followed by improper duration and incorrect choice of prophylactic method.…”

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confidence: 53%

Profilaxia da trombose venosa profunda: aplicação prática e conhecimento teórico em um hospital geral

Pereira

Brito²,

Martins³

et al. 2008

J. vasc. bras.

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confidence: 53%

Profilaxia da trombose venosa profunda: aplicação prática e conhecimento teórico em um hospital geral

Pereira

Brito²,

Martins³

et al. 2008

J. vasc. bras.

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“…Not only is VTE the third most common cause of all hospitalrelated deaths 2) , it is also the most common preventable cause of hospital death 3) . Despite substantial evidence that VTE prophylaxis can reduce the incidence of VTE, prophylactic treatment remains largely underused in hospitalized patients [4][5][6][7] . Accurately assessing the risk of VTE is critical for improving this situation and increasing compliance with prophylaxis guidelines.…”

Section: Introductionmentioning

confidence: 99%

Validation of a Venous Thromboembolism Risk Assessment Model in Hospitalized Chinese Patients: A Case-Control Study

Zhou

Wang

et al. 2014

JAT

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Aim: The appropriate selection of hospitalized patients for venous thromboembolism (VTE) prophylaxis is an important unresolved issue. We sought to validate the Caprini model, a famous individual VTE risk assessment model (RAM), in hospitalized Chinese patients. Methods: We performed a retrospective case-control study among unselected hospitalized patients admitted to a comprehensive hospital in China. A total of 347 patients were confirmed to have VTE during hospitalization, and 651 controls were randomly selected to match the patients according to medical service. Both the patients and controls were retrospectively assessed for the risk of VTE using the Caprini RAM. Results: The average Caprini cumulative risk score in the patients was significantly higher than that observed in the controls (4.69±2.58 vs 3.16±1.82, p＜0.0001). Compared with that observed in the low-risk group, a classification of high-risk according to the Caprini model was associated with a 1.65-fold increased risk of VTE (95%CI 1.05-2.61), while that of highest-risk was associated with a 4.84-fold increased risk of VTE (95%CI 3.06-7.64). After further stratifying the highest risk level with a cumulative risk score of ≥ 5 into scores of 5-6, 7-8 and ≥ 9, the patients with a score of 5-6 were found to exhibit a 3.33-fold increased risk of VTE (95%CI 2.06-5.40), those with a score 7-8 exhibited a 9.41-fold increased risk of VTE (95%CI 4.90-18.08) and those with a score of ≥ 9 exhibited a 24.69-fold (95%CI 7.98-76.40) increased risk of VTE compared with their low-risk counterparts. Conclusions: Our study suggests that the Caprini RAM can be used to effectively stratify hospitalized Chinese patients into VTE risk categories based on individual risk factors. The classification of the highest risk level with a cumulative risk score of ≥ 5 provided significantly more clinical information, and further stratification of this group of patients is needed. J Atheroscler Thromb, 2014; 21:261-272.

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“…In a recent survey, The Fundamental Research in Oncology and Thrombosis (FRONTLINE), marked differences were seen in the use of thromboprophylaxis for surgical and medical cancer patients, with over 50% of surgeons reporting that they initiated thromboprophylaxis routinely, while most medical oncologists reported using thromboprophylaxis in less than 5% of medical cancer patients (Kakkar et al, 2003). These studies and many others (Chopard et al, 2005;Ageno et al, 2002), demonstrate that VTE prophylaxis in cancer patients is still underutilized.…”

Section: Making the Decisionmentioning

confidence: 99%

Venous Thromboembolism Prophylaxis in Cancer Patients

Abdel‐Razeq¹

2012

Deep Vein Thrombosis

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Venous thromboembolism prophylaxis in acutely ill medical patients: definite need for improvement

Abstract: Abstract. Chopard P,

Cited by 83 publications

References 16 publications

Profilaxia da trombose venosa profunda: aplicação prática e conhecimento teórico em um hospital geral

Profilaxia da trombose venosa profunda: aplicação prática e conhecimento teórico em um hospital geral

Validation of a Venous Thromboembolism Risk Assessment Model in Hospitalized Chinese Patients: A Case-Control Study

Venous Thromboembolism Prophylaxis in Cancer Patients

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