In a 1,4-dioxane-water mixture at 293, 295, and 297 K, throughout a wide range of concentration, the density, viscosity, and ultrasonic velocity of synthesised Schiff base 1,3-benzothiazol-2-amine and its substituted derivatives have been examined. The current work involved the analysis of acoustical parameters such as ultrasonic velocity (V), adiabatic compressibility (βs), apparent molar volume (ϕv), and intermolecular free length (Lf), which represent structural properties.