Ventilator-Associated Pneumonia Is an Important Risk Factor for Mortality After Major Cardiac Surgery

Tamayo, Eduardo; Álvarez, Francisco; Martínez-Rafael, Beatriz; Bustamante, Juan; Bermejo-Martín, Jesús F.; Fierro, I.; Eirós, José María; Castrodeza, Javier; Heredia, María

doi:10.1097/01.sa.0000422674.20605.f1

Cited by 12 publications

(20 citation statements)

References 19 publications

(39 reference statements)

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“…Another prospective study from Spain looked at 1610 adult cardiac surgical patients, all of whom had undergone surgery on cardiopulmonary bypass (CPB). In this population, the incidence of VAP was 7.7% and the mortality associated with VAP was 49.2% . None of these studies related duration of ventilation and the development of VAP.…”

Section: Incidence Of Vapmentioning

confidence: 79%

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Incidence, Risk, and Prevention of Ventilator-Associated Pneumonia in Adult Cardiac Surgical Patients: A Systematic Review

Fitch

Whitman

2013

J Card Surg

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Section: Incidence Of Vapmentioning

confidence: 79%

“…In this population, the incidence of VAP was 7.7% and the mortality associated with VAP was 49.2%. 19 None of these studies related duration of ventilation and the development of VAP.…”

Section: Incidence Of Vapmentioning

confidence: 99%

Incidence, Risk, and Prevention of Ventilator-Associated Pneumonia in Adult Cardiac Surgical Patients: A Systematic Review

Fitch

Whitman

2013

J Card Surg

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“…Ventilation-associated pneumonia (VAP) is one of the most important risk factors for hospital mortality in cardiac surgery patients [16]. Oronasopharyngeal decontamination with chlorhexidine has proven to be an effective method to reduce the VAP rate in these patients [17] and should be a routine measure.…”

Section: Ventilation-associated Pneumoniamentioning

confidence: 99%

Preventing and managing perioperative pulmonary complications following cardiac surgery

García-Delgado

Navarrete-Sánchez²,

Colmenero³

2014

Current Opinion in Anaesthesiology

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Postoperative pulmonary complications are common, but severe complications are infrequent. Their reduction requires measures to prevent infection and mechanical ventilation-associated lung injury through the use of low tidal volumes and early extubation. Noninvasive ventilation after extubation can be utilized to avoid reintubation and the associated increased morbidity and mortality. However, noninvasive ventilation should be done under rigorous conditions and by following strict criteria.

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“…According to reports by Melsen et al, the mortality rate of children caused by VAP is 13% . The mortality rate of patients with VAP and high risk factors, such as those after CHD surgery, can be up to 49.2% …”

Section: Discussionmentioning

confidence: 99%

Predictive value of C‐reactive protein and the Pediatric Risk of Mortality III Score for occurrence of postoperative ventilator‐associated pneumonia in pediatric patients with congenital heart disease

Sun

Zhao

Dong

et al. 2019

Pediatric Investigation

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Importance Ventilator‐associated pneumonia (VAP) is one of the most common complications after cardiac surgery in children with congenital heart disease (CHD). Early prediction of the incidence of VAP is important for clinical prevention and treatment. Objective To determine the value of serum C‐reactive protein (CRP) levels and the Pediatric Risk of Mortality III (PRISM III) score in predicting the risk of postoperative VAP in pediatric patients with CHD. Methods We performed a retrospective review of clinical data of 481 pediatric patients with CHD who were admitted to our pediatric intensive care unit. These patients received mechanical ventilation for 48 hours or longer after corrective surgery. On the basis of their clinical manifestations and laboratory results, patients were separated into two groups of those with VAP and those without VAP. CRP levels were measured and PRISM III scores were collected within 12 hours of admission to the pediatric intensive care unit. The Pearson correlation coefficient was used to evaluate the association of CRP levels and the PRISM score with the occurrence of postoperative VAP. A linear regression model was constructed to obtain a joint function and receiver operating curves were used to assess the predictive value. Results CRP levels and the PRISM III score in the VAP group were significantly higher than those in the non‐VAP group (P < 0.05). Receiver operating curves suggested that using CRP + the PRISM III score to predict the incidence of VAP after congenial heart surgery was more accurate than using either of them alone (CRP + the PRISM III score: sensitivity: 53.2%, specificity: 85.7%). When CRP + the PRISM III score was greater than 45.460, patients were more likely to have VAP. Interpretation Although using CRP levels plus the PRISM III score to predict the incidence of VAP after congenial heart surgery is more accurate than using either of them alone, its predictive value is still limited.

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Ventilator-Associated Pneumonia Is an Important Risk Factor for Mortality After Major Cardiac Surgery

Cited by 12 publications

References 19 publications

Incidence, Risk, and Prevention of Ventilator-Associated Pneumonia in Adult Cardiac Surgical Patients: A Systematic Review

Incidence, Risk, and Prevention of Ventilator-Associated Pneumonia in Adult Cardiac Surgical Patients: A Systematic Review

Preventing and managing perioperative pulmonary complications following cardiac surgery

Predictive value of C‐reactive protein and the Pediatric Risk of Mortality III Score for occurrence of postoperative ventilator‐associated pneumonia in pediatric patients with congenital heart disease

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