“…We recognized that lack of quantitative exposure levels, inherent to the data available, is a major limitation of the study. Previous studies have provided strong evidence for an exposure-response relation between cumulative exposure to dust and pulmonary function decrements [Morgan et al, 1974;Soutar and Seixas et al, 1993]. The study using years working underground as a surrogate of cumulative exposure might not be sufficient to explore a truly causal association between simple CWP and decrements in pulmonary function.…”
“…We recognized that lack of quantitative exposure levels, inherent to the data available, is a major limitation of the study. Previous studies have provided strong evidence for an exposure-response relation between cumulative exposure to dust and pulmonary function decrements [Morgan et al, 1974;Soutar and Seixas et al, 1993]. The study using years working underground as a surrogate of cumulative exposure might not be sufficient to explore a truly causal association between simple CWP and decrements in pulmonary function.…”
“…5 However, residual volume correlated with roentgenographic changes even in subjects free of airways obstruction. In nonsmoking subjects with category 2 or 3 roentgenographic changes, frequency dependence of compliance can be demonstrated regardless of whether or not the subject has bronchitic symptoms.…”
Section: Correlation Of Roentgenographic Changesmentioning
“…In an early analysis based on the first round of surveys, Morgan and colleagues found decrements in FEV 1 and forced vital capacity (FVC) in relation to years worked underground among non-smoking miners who did not have complicated pneumoconiosis 13. However, the trend was inconsistent between regions and they dismissed it as inconsequential.…”
Section: Symptoms Lung Function and Dust Exposure In Coal Minersmentioning
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