Ventilatory Studies in Healthy Infants

Phelan, P. D.; Williams, Howard E.

doi:10.1203/00006450-196909000-00005

Cited by 48 publications

(32 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in our previous study, the values of pulmonary functions reported in this work showed good agreement with data in other studies (3,5,7,10,11,15). The increased ventilation during carbon dioxide-induced hyperventilation was due mainly to an increased tidal volume.…”

Section: Discussionsupporting

confidence: 82%

See 1 more Smart Citation

Pulmonary Mechanics in Early Infancy. Sublinical Grunting in Low-Birth-Weight Infants

et al. 1981

View full text Add to dashboard Cite

SummaryPulmonary mechanics were studied with the constant pressure body plethysmograph method in 78 infants during the first year of life. Registrations of breathing frequency, tidal volume, minute volume, dynamic compliance, pulmonary functional resistance, and end-expiratory resistance were made at rest and during carbon dioxide-induced hyperventilation. Data from 70 infants demonstrated strong correlations (P < 0.001) between all pulmonary function parameters and length. Carbon dioxide-induced hyperventilation was achieved mainly by an increased tidal volume. Pulmonary functional resistance did not change with hyperventilation, indicating wider airways during forced ventilation.A special breathing pattern called "subclinical grunting" was found in 16 of 45 infants who were low birth weight but without clinical signs of hyaline membrane disease. The pattern was characterized by a high resistance during most of the prolonged expiration. It was identical to that previously described in cases of hyaline membrane diseases. All re-examined low-birth-weight infants with subclinical grunting developed a normal breathing pattern. SpeculationSublinical grunting found in preterm low-birth-weight infants might be a phenomenon of postnatal lung adaptation which can be registered by pulmonary mechanics examination.

show abstract

Section: Discussionsupporting

confidence: 82%

“…Pulmonary mechanics studies have been reported for both newborn (3,4,7,8,13,14) and older infants (5,10,11,13,15). In a previous study of pulmonary mechanics, we studied 26 infants during the first year of life (2).…”

mentioning

confidence: 99%

Pulmonary Mechanics in Early Infancy. Sublinical Grunting in Low-Birth-Weight Infants

et al. 1981

View full text Add to dashboard Cite

show abstract

“…during active sleep in normal fullterm infants. Normal ranges for lung mechanics have also been reported in the same young age group and most of these studies have been performed in the supine posture (16,24,25,26,28).…”

Section: Discussionmentioning

confidence: 99%

“…Measurements can be made by whole body plethysmography (2,7,13,21,24,26,28), (Thoracic Gas Volume, T.G.V.) or by gas dilution (6,30).…”

Section: Discussionmentioning

confidence: 99%

Lung Volume and Lung Mechanics in Infancy Lateral or Supine Posture?

1982

View full text Add to dashboard Cite

“…David HendersonSmart subsequently continued these important studies in Sydney. In Melbourne, Peter Phelan, who trained with Howard Williams, began making his own special contribution to documenting lung function in children (19).…”

Section: The 1950s-1960s: the "Founding Fathers" Emergementioning

confidence: 99%