Venting the Spleen

Varughese, Neal; Duong, Angie; Emre, Sukru; Xu, Mina L.; Lee, Alfred Ian

doi:10.1056/nejmcps1210943

Cited by 7 publications

(2 citation statements)

References 12 publications

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“…On the other hand, this case presented intense acute inflammation of unknown cause; some kind of strong infection or immunological response might have triggered the atraumatic rupture of the exaggerated splenic tissue. In patients who underwent splenectomy because of a chronic hemolytic disorder or immune thrombocytopenia, ectopic splenic tissue such as splenosis can result in recurrence of them [ 15 ]. Our case presented the elevation of indirect bilirubin which may indicate recurrence of hereditary spherocytosis due to the enlargement of the splenic tissue.…”

Section: Case Presentationmentioning

confidence: 99%

Spontaneous hemorrhage from splenic tissue 13 years after total splenectomy: report of a case

et al. 2015

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A 33-year-old man suffered sudden abdominal distension without traumatic episodes. He had undergone total splenectomy for hereditary spherocytosis 13 years ago. He was in shock, and his hemoglobin level was 10.5 g/dl. Contrast enhanced computed tomography revealed a giant mass in the left upper abdomen and extravasation of the contrast material into the mass. Excision of the mass was performed, and microscopic examination showed a giant hematoma surrounded by normal splenic tissue. We speculated that an accessory spleen or splenosis had enlarged for the 13 years and ruptured. The patient remained asymptomatic 4 months after the surgery. Spontaneous hemorrhage from accessory spleens or splenosis is extremely rare, and relevant case reports suggest that surgical resection of bleeding sites yields favorable prognosis although preoperative qualitative diagnosis seems to be difficult.

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Section: Case Presentationmentioning

confidence: 99%

Spontaneous hemorrhage from splenic tissue 13 years after total splenectomy: report of a case

et al. 2015

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“…Diagnosis is often challenging and should be considered whenever intraperitoneal nodules of uncertain significance are incidentally found decades after splenectomy, possibly raising a misleading suspicion of malignancy 7. Most patients are asymptomatic, but complications including haemorrhage, pain or bowel obstruction can rarely occur 8. Of note, splenosis can sometimes functionally revert asplenia when the ectopic splenic mass is higher than 20–30 cm 3 , resulting in the disappearence of erythrocytes Howell-Jolly bodies on peripheral blood smear 4.…”

Section: Introductionmentioning

confidence: 99%

Unusual case of iron overload with cancer-mimicking abdominal splenosis

Marchi¹,

Avesani

Zamò

et al. 2018

BMJ Case Reports

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A 48-year-old man, former alcohol abuser and drug addicted, was referred to our tertiary referral centre for iron disorders because of marked hyperferritinaemia. His clinical history revealed chronic hepatitis C, ß-thalassaemia trait and post-traumatic splenectomy at age of 22. MRI-estimated liver iron content was markedly elevated, while first-line genetic test for haemochromatosis was negative. Alpha-fetoprotein was increased but liver ultrasonography did not reveal focal liver lesions. Multiphasic contrast-enhanced CT confirmed this result but showed two abdominal masses (diameter of 9 cm and 7 cm, respectively) among bowel loops, strongly suspicious for cancer. However, biopsy of one of the masses led to the final diagnosis of abdominal splenosis.

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Selektive Chirurgie der Milz

Pozios

Seeliger

2022

Springer Reference Medizin

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Venting the Spleen

Cited by 7 publications

References 12 publications

Spontaneous hemorrhage from splenic tissue 13 years after total splenectomy: report of a case

Spontaneous hemorrhage from splenic tissue 13 years after total splenectomy: report of a case

Unusual case of iron overload with cancer-mimicking abdominal splenosis

Selektive Chirurgie der Milz

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