Ventricular Arrhythmias and Sudden Death in Nonischemic Dilated Cardiomyopathy: Matter of Sex or Scar?

Marco, Andrea Di; Brown, Pamela Frances; Claver, Eduard; Bradley, Joshua; Nucifora, Gaetano; Ruiz‐Cueto, María; Dallaglio, Paolo; Rodriguez, Marcos; Comín‐Colet, Josep; Anguera, Ignasi; Miller, Christopher A.; Schmitt, Matthias

doi:10.1016/j.cardfail.2022.01.019

Cited by 2 publications

(3 citation statements)

References 14 publications

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“…Prospective cohort studies have shown that the incidence of ventricular arrhythmias increases with age [0.5 vs 0.3 per 1000 population in age group >65 years compared to <65 years] and are more prevalent in men [0.59% in men compared to 0.2% in women over 65] [5]. In patients with nonischemic cardiomyopathy, the prevalence of late gadolinium enhancement is also higher in men compared to women [4,6]. These factors may explain the gender differences in mortality related to ventricular tachycardia.…”

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confidence: 99%

Increasing Trend in Ventricular Tachycardia Related Mortality- Cause or Effect?

Balakrishnan

Hutchinson

2023

Preprint

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Ventricular tachycardia is a major cause of sudden death. Several pharmacological and device-based therapies in recent years have delayed the progression of heart failure and have improved survival. A new study reveals a significant increase in age-adjusted mortality from ventricular tachycardia over the past 13 years, with higher mortality in men, black Americans and patients from the Southern United States. These findings reinforce the previous observations made on the influence of age, gender, ethnicity and geography on cardiovascular outcomes. The use of ICD 10 codes to ascertain cause of death limits differentiation between ventricular tachycardia as the true underlying mechanism leading to death and the presence of ventricular tachycardia in patients dying from other causes. While the insights gained from the report on contemporary ventricular tachycardia related mortality in the general population with cardiovascular disease is hypothesis generating, further studies are needed to delineate ventricular tachycardia as a proximate cause of death from an association.

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confidence: 99%

Increasing Trend in Ventricular Tachycardia Related Mortality- Cause or Effect?

Balakrishnan

Hutchinson

2023

Preprint

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“…5 In patients with nonischemic cardiomyopathy, the prevalence of late gadolinium enhancement is also higher in men compared to women. 4,6 These factors may explain the gender differences in mortality related to ventricular tachycardia. Ethnic disparities in heart failure outcomes have been documented in multiple studies including CARDIA and MESA, with worse heart failure outcomes in black populations across age groups.…”

mentioning

confidence: 99%

“…Prospective cohort studies have shown that the incidence of ventricular arrhythmias increases with age [0.5 vs. 0.3 per 1000 population in age group >65 years compared to <65 years] and are more prevalent in men [0.59% in men compared to 0.2% in women over 65] 5 . In patients with nonischemic cardiomyopathy, the prevalence of late gadolinium enhancement is also higher in men compared to women 4,6 . These factors may explain the gender differences in mortality related to ventricular tachycardia.…”

mentioning

confidence: 99%