Ventricular arrhythmias during Tako-tsubo syndrome

Is abnormal myocardial repolarization associated with the occurrence of malignant tachyarrhythmias in Takotsubo cardiomyopathy?

“…In January 2008 we also contacted 7 authors who had previously published cases or case series with ventricular tachyarrhythmias in TC to contribute data from their published and, if available, from additional unpublished patients to the study. Overall, 5 authors contributed data from 20 patients with TC and malignant ventricular tachyarrhythmias [5][6][7][8][9]. Of these, 1 patient was excluded because of poor ECG quality that prohibited further analysis.…”

Severe Multivessel Coronary Vasospasm and Left Ventricular Ballooning Syndrome

“…We assume that this was due to recurrence of severe vasospasm in the right coronary artery. Third, incessant ventricular fibrillation, although rare in TC, has been previously reported as a cause of death in the disease, 3 but its cause remains obscure. Finally, the potential induction of vasospasm from epinephrine injections during cardiac arrest should also be kept in mind.…”

Transient Cardiac Ballooning—The Syndrome

“…13 -15 Recently though, a rather higher incidence (around 15%) of fatal ventricular arrhythmias has been reported in a small series. 16 Acute thromboembolism has also been encountered in 3 out of 21 affected individuals in a small European series. 17 Two of these 3 patients experienced embolic stroke within the first 48 hours.…”

“…32 A recent systematic review reported the incidence of 2.5% for LV thrombus formation in patients with TCBS, but the thromboembolic complications were 0.8% and did not result in any fatal outcomes or the need for surgery. 17 Although life threatening, ventricular arrhythmias have been reported acutely, 15,16 there is no data incorporating the use of antiarrhythmic therapy or intracardiac defibrillator (ICD). The decision to implant an ICD could be considered based on other risk factors if the LVEF is still low after 6 to 8 weeks on maximal medical therapy.…”