Ventricular Assist Devices and Their Usage as a Bridge to Recovery in Patients With Acute Cardiotoxicity and Cardiomyopathy

Abstract

Cardiotoxicity can reduce the heart's function temporarily and is most commonly caused by radiation, immune reactions, and certain medications. Using a left ventricular assist device (LVAD) as a bridging therapy while waiting for cardiac recovery has been popular lately in patients who have a reduced ejection fraction after significant cardiac injury. Here we analyze the use of LVAD as a bridging therapy in three cases with chemotherapy-induced cardiotoxicity, acute myocarditis, and postpartum cardiac failure. Although LVADs are infamous for their device-related complications, the ejection fraction can increase up to 50% within days to months of usage without any complications in acute cardiotoxic patients that have no underlying significant risk factors or co-morbidities. Hence LVADs are excellent supportive devices while waiting for cardiac recovery, both in maintaining cardiac function and improving the associated organ failures.

Impacts of Land Use and Land Cover Changes on Land Surface Temperature over Cachar Region, Northeast India—A Case Study

“…As already established, LULC alteration is mostly the result of human activity, particularly agricultural and urban expansion [4]. Due to the effects brought on by environmental, political, social, and economic factors, human influence on LULC has a dynamic and nonlinear nature [5,6]. The variation in climate, which can itself be a result of anthropogenic influences, is one of the other main causes of changes in LULC [7].…”