Ventricular Fibrillation in Induced Hypothermia

Caldini, Paolo

doi:10.1136/pgmj.35.408.538

Cited by 5 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In accordance with these findings, hypothermia of 30°C increased the vulnerability to pacing‐induced ventricular fibrillation by facilitating wave breaks and promoting the onset of ADP alternans in Langendorff‐perfused isolated rabbit hearts . The increased incidence of ventricular fibrillation, which is frequently observed in patients suffering from accidental hypothermia, was also experimentally confirmed in vivo in a porcine model …”

Section: Discussionsupporting

confidence: 73%

Mild hypothermia (33°C) increases the inducibility of atrial fibrillation: An in vivo large animal model study

Manninger

Alogna

Zweiker

et al. 2018

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 73%

Mild hypothermia (33°C) increases the inducibility of atrial fibrillation: An in vivo large animal model study

Manninger

Alogna

Zweiker

et al. 2018

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

“…Hypothermia and rewarming from hypothermia are known to induce Ventricular Fibrillation. [24,25] It is likely that rewarming efforts during CPR contribute to the rhythm conversion.…”

Section: Discussionmentioning

confidence: 99%

“…Hypothermia and rewarming from hypothermia are known to induce Ventricular Fibrillation. [24,25] It is likely that rewarming efforts during CPR contribute to the rhythm conversion. In hypothermic OHCA, unlike general OHCA, defibrillation after rhythm conversion was not associated with better outcomes.…”

Section: Discussionmentioning

confidence: 99%

Associations between prehospital defibrillation and outcomes of out-of-hospital cardiac arrests presumed to be caused by hypothermia: A nationwide observational study with epidemiological analysis

et al. 2023

View full text Add to dashboard Cite

This study aimed to clarify the epidemiology of out of-hospital cardiac arrest (OHCA) cases caused by hypothermia. The associations between the presence/absence of shockable initial electrocardiography rhythm, prehospital defibrillation and the outcomes of OHCA were also investigated. This study involved the retrospective analysis of prospectively collected, nationwide, population-based data for OHCA cases caused by hypothermia. One thousand five hundred seventy-five emergency medical service (EMS)-confirmed OHCA cases with hypothermia, recorded between 2013 and 2019, were extracted from the Japanese nationwide database. The primary outcome was neurologically favorable 1-month survival, defined as cerebral performance category 1 or 2. The secondary outcome was 1-month survival. OHCA cases with hypothermia occurred more frequently in the winter. In approximately half (837) of the hypothermic OHCA cases, EMS was activated in the morning (6:00 am to 11:59 am). Shockable initial electrocardiogram rhythms were recorded in 30.8% (483/1570) of cases. prehospital defibrillation was attempted in 96.1% (464/483) of cases with shockable rhythms and 25.8% (280/1087) of cases with non-shockable initial rhythms. EMS-witnessed cases, prolonged transportation time intervals and prehospital epinephrine administration were associated with rhythm conversion in cases with non-shockable initial rhythms. Binominal logit test followed by multivariable logistic regression revealed that shockable initial rhythms were associated with better outcomes. prehospital defibrillation was not significantly associated with better outcomes, regardless of the type of initial rhythm (shockable or non-shockable). Transportation to high-level emergency hospitals was associated with better outcomes (adjusted odds ratio: 2.94, 95% confidence interval: 1.66–5.21). In hypothermic OHCA, shockable initial rhythm but not prehospital defibrillation is likely to be associated with better neurologically favorable outcomes. In addition, transport to a high-level acute care hospital may be appropriately considered despite prolonged transport. Further investigation, including core temperature data in analyses, is necessary to determine the benefit of prehospital defibrillation in hypothermic OHCA.

show abstract

“…It has also been known for more than a half century that induced hypothermia for surgical procedures led to VF in humans. 26) 27) Historically, quinidine was used to prevent VF in patients who required hypothermia for surgical procedures. 28) We now know that quinidine prevents and suppress VF in JWS via suppressing I to .…”

Section: J Wave and Early Repolarization: Vaguely Defined Terms And Cmentioning

confidence: 99%

J Wave Syndromes: History and Current Controversies

2016

View full text Add to dashboard Cite

The concept of J wave syndromes was first proposed in 2004 by Yan et al for a spectrum of electrocardiographic (ECG) manifestations of prominent J waves that are associated with a potential to predispose affected individuals to ventricular fibrillation (VF). Although the concept of J wave syndromes is widely used and accepted, there has been tremendous debate over the definition of J wave, its ionic and cellular basis and arrhythmogenic mechanism. In this review article, we attempted to discuss the history from which the concept of J wave syndromes (JWS) is evolved and current controversies in JWS.

show abstract

Ventricular Fibrillation in Induced Hypothermia

Abstract: First proposed by Bigelow et al. (1950), the clinical use of hypothermia has become more widespread in the last eight years. Due

Cited by 5 publications

References 19 publications

Mild hypothermia (33°C) increases the inducibility of atrial fibrillation: An in vivo large animal model study

Mild hypothermia (33°C) increases the inducibility of atrial fibrillation: An in vivo large animal model study

Associations between prehospital defibrillation and outcomes of out-of-hospital cardiac arrests presumed to be caused by hypothermia: A nationwide observational study with epidemiological analysis

J Wave Syndromes: History and Current Controversies

Contact Info

Product

Resources

About