Venue-Based HIV Testing at Sex Work Hotspots to Reach Adolescent Girls and Young Women Living With HIV: A Cross-sectional Study in Mombasa, Kenya

Ma, Huiting; Wang, Linwei; Gichangi, Peter; Mochache, Vernon; Manguro, Griffins; Musyoki, Helgar; Bhattacharjee, Parinita; Cholette, François; Sandstrom, Paul; Becker, Marissa; Mishra, Sharmistha

doi:10.1097/qai.0000000000002363

Cited by 17 publications

(16 citation statements)

References 30 publications

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“…Second, most models assumed equal ART cascade transition rates across subgroups, including diagnosis, ART initiation, and retention. Recent data suggest differential ART cascade by sex, age, and key populations [30, 54, 55, 21]. These differences may stem from the unique needs of population subgroups and is one reason why differentiated ART services are a core component of HIV programs [56, 57].…”

Section: Discussionmentioning

confidence: 99%

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

Knight

Kaul

Mishra

2021

Preprint

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Objective. Transmission models provide complementary evidence to clinical trials about the potential population-level incidence reduction attributable to ART (ART prevention impact). Different modelling assumptions about risk heterogeneity may influence projected ART prevention impacts. We sought to review representations of risk heterogeneity in compartmental HIV transmission models applied to project ART prevention impacts in Sub-Saharan Africa. Design. Scoping review to identify common modelling assumptions and applications. Methods. We systematically reviewed studies published before January 2020 that used non-linear compartmental models of sexual HIV transmission to simulate ART prevention impacts in Sub-Saharan Africa. We summarized data on model structure/assumptions (factors) related to risk and intervention heterogeneity, and explored crude associations of ART prevention impact with modelled factors. Results. Of 1384 search hits, 94 studies were included, which primarily modelled medium/high prevalence epidemics in East/Southern Africa. 64 studies considered sexual activity stratification and 39 modelled at least one key population. 21 studies modelled faster/slower ART cascade transitions (HIV diagnosis, ART initiation, or cessation) by risk group, including 8 with faster and 4 with slower cascade transitions among key populations versus the wider population. Models without activity stratification predicted the largest ART prevention impacts, followed by models with key populations that had faster cascade transitions versus the wider population. Conclusions. Among compartmental transmission models applied to project ART prevention impacts, representations of risk heterogeneity and projected impacts varied considerably, where models with less heterogeneity tended to predict larger impacts. The potential influence of modelling assumptions about risk and intervention heterogeneity should be further explored.

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Section: Discussionmentioning

confidence: 99%

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

Knight

Kaul

Mishra

2021

Preprint

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“…The questionnaire was developed for the purpose of this study, and pilot-tested with local community and programmatic input, and data were collected in partnership with the International Centre for Reproductive Health Kenya. Details of the data collection have been detailed previously [11,25,26].…”

Section: Study Design and Data Collectionmentioning

confidence: 99%

Low program access despite high burden of sexual, structural, and reproductive health vulnerabilities among young women who sell sex in Mombasa, Kenya

Roberts

Bhattacharjee

et al. 2020

BMC Public Health

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Background: Across Sub-Saharan Africa, young women who sell sex (YSW) face institutional barriers in accessing sexual health and HIV prevention programs designed for female sex workers. In 2018, Kenya developed a national framework to guide service provision for YSW aged 14-24 years. To help inform the implementation of the framework, we estimated the burden of vulnerabilities related to the Sustainable Development Goals (SDGs related to health and gender equality) and program contact among YSW. Methods: We used data from Transitions, a 2015 bio-behavioural cross-sectional survey of 408 YSW aged 14-24 years in Mombasa, Kenya. We estimated the prevalence of sexual (inconsistent condom use), structural (financial, violence), and reproductive health vulnerabilities; and characterized engagement with local HIV programs tailored to sex workers. We then compared the prevalence of vulnerabilities by age group (14-18 years, N = 117; 19-24 years, N = 291) and by program contact (ever contacted by local program for sex workers). Results: 47.3% reported inconsistent condom use with any partner in the previous week (no difference by agegroup, p = 1.00). Structural vulnerabilities were common and did not vary by age: 83.6% did not have a regular source of income; 29.9 and 29.2% had experienced physical and sexual violence, respectively. 26.5% reported at least one pregnancy before age 18, and 18.5% used a non-reliable form of contraception with little variability by age. 25.7% were aware of at least one program, and only 13.7% of YSW had ever been contacted by a program (8.5% of those aged 14-18 years; and 15.8% of those aged 19-24 years, p = 0.06). Sexual, structural, and reproductive health vulnerabilities did not vary by program contact.

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“…Various approaches, such as integration of HIV testing services with other health services ( Narasimhan et al., 2019 ), and community-based testing within sex work hotspots and at drop-in centres (DICs) ( Mulongo et al., 2015 ; Pande et al., 2019 ; Ma et al., 2020 ), have been implemented and shown to improve access to routine HIV testing among FSWs ( Bassett et al., 2015 ).…”

Section: Introductionmentioning

confidence: 99%

Factors associated with adherence to HIV testing guidelines among HIV-negative female sex workers in Kampala, Uganda

et al. 2022

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Venue-Based HIV Testing at Sex Work Hotspots to Reach Adolescent Girls and Young Women Living With HIV: A Cross-sectional Study in Mombasa, Kenya

Abstract: Supplemental Digital Content is Available in the Text.

Cited by 17 publications

References 30 publications

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

Risk heterogeneity in compartmental HIV transmission models of ART as prevention in Sub-Saharan Africa: A scoping review

Low program access despite high burden of sexual, structural, and reproductive health vulnerabilities among young women who sell sex in Mombasa, Kenya

Factors associated with adherence to HIV testing guidelines among HIV-negative female sex workers in Kampala, Uganda

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