Verbal Fluency Test in Children with Neurodevelopmental Disorders

Paz, Esteban Vaucheret; Puga, Celeste; Ekonen, Christy; Pintos, Paula; Lascombes, Isabel; Vita, Soledad De; Leist, Mariana; Corleto, Mariela; Básalo, María José García

doi:10.1055/s-0039-3400347

Cited by 10 publications

(7 citation statements)

References 22 publications

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“…The TMT consists of two subtests: TMT-A mainly assesses motor speed and visual search skills, while TMT-B reflects cognitive flexibility. Furthermore, the Digit Symbol Substitution Test (DSST) (Rosano et al, 2013) and Verbal Fluency Test (VFT) (Vaucheret Paz et al, 2020) were used to measure both the mental operating speed and visuospatial abilities. Additionally, the symptoms of anxiety and depression were evaluated by the hospital anxiety and depression scale (Pais-Ribeiro et al, 2018).…”

Section: Cognitive Assessmentmentioning

confidence: 99%

Abnormal Static and Dynamic Functional Network Connectivity in Patients With Presbycusis

Xing

Chen

Shang

et al. 2022

Front. Aging Neurosci.

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Aim: This study aimed to investigate abnormal static and dynamic functional network connectivity (FNC) and its association with cognitive function in patients with presbycusis.Methods: In total, 60 patients with presbycusis and 60 age-, sex-, and education-matched healthy controls (HCs) underwent resting-state functional MRI (rs-fMRI) and cognitive assessments. Group independent component analysis (ICA) was carried out on the rs-fMRI data, and eight resting-state networks (RSNs) were identified. Static and dynamic FNCs (sFNC and dFNC) were then constructed to evaluate differences in RSN connectivity between the patients with presbycusis and the HCs. Furthermore, the correlations between these differences and cognitive scores were analyzed.Results: Patients with presbycusis had differences in sFNC compared with HCs, mainly reflected in decreased sFNC in the default mode network (DMN)-left frontoparietal network (LFPN) and attention network (AN)-cerebellum network (CN) pairs, but they had increased sFNC in the auditory network (AUN) between DMN domains. The decreased sFNC in the DMN-LFPN pair was negatively correlated with their TMT-B score (r = –0.441, p = 0.002). Patients with presbycusis exhibited aberrant dFNCs in State 2 and decreased dFNCs between the CN and AN and the visual network (VN). Moreover, the presbycusis group had a shorter mean dwell time (MDT) and fraction time (FT) in State 3 (p = 0.0027; p = 0.0031, respectively).Conclusion: This study highlighted differences in static and dynamic functional connectivity in patients with presbycusis and suggested that FNC may serve as an important biomarker of cognitive performance since abnormal alterations can better track cognitive impairment in presbycusis.

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Section: Cognitive Assessmentmentioning

confidence: 99%

Abnormal Static and Dynamic Functional Network Connectivity in Patients With Presbycusis

Xing

Chen

Shang

et al. 2022

Front. Aging Neurosci.

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“…[31][32][33] Therefore, our findings may not apply to women; Psychological stress factors were evaluated based on self-rated scores. We did not evaluate participants psychological stress based on a structured diagnostic interview (e.g., a Structured Clinical Interview for Diagnostic and Statistical Manual diagnoses [34] ); We did not consider the participants intelligence quotient, which may have influenced the VFT; [35] Because the study was conducted in participants who were able to apply through recruitment posters, there is a possibility that this study population does not clearly represent healthy Japanese males. However, as all candidates who met the inclusion criteria participated in our study, there were no arbitrary selection biases.…”

Section: Discussionmentioning

confidence: 99%

Correlation between trait emotional intelligence and prefrontal activation during a verbal fluency task: A functional near-infrared spectroscopy study

et al. 2023

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Stress is inevitable in humans and stress changes our physical and mental states. Stress has been studied epidemiologically, biologically, and psychologically. First defined in 1990, emotional intelligence (EI) affects psychological stress management. In contrast, the prefrontal cortex (PFC) is suggested to play a vital role in stress management. Human PFC activity can be inferred from the balance of oxygenated and deoxygenated hemoglobin in cerebral blood flow, which can be measured and calculated using functional near-infrared spectroscopy (fNIRS). An important cognitive activation task to activate the PFC is the verbal fluency task (VFT). Therefore, if the PFC is activated by the VFT and monitored by fNIRS, and the activity correlates with EI, fNIRS can be used to measure EI. In this study, Psychological tests using the self-rating depression scale, state-trait anxiety inventory (STAI), and trait emotional intelligence questionnaire-short form (TEIQue-SF) were conducted to evaluate the correlation with VFT performance. Relative oxygenated and deoxygenated hemoglobin concentrations were measured using an fNIRS device, and their correlation with VFT performance was tested. Spearman correlation coefficient was used to determine correlations. Results were as follows. Although VFT performance did not correlate with the oxygenated hemoglobin concentration ([Oxy-Hb]) changes, [Oxy-Hb] was elevated in all channels. VFT performance was significantly negatively correlated with the Zung self-rating depression scale (ρ = 0.063, P = .759), trait anxiety or anxiety level as a personal characteristic of STAI (ρ = 0.243, P = .232), and state anxiety or anxiety about an event of STAI (ρ = −0.138, P = .500), whereas no correlation was found with the TEIQue-SF (ρ = 0.303, P = .132). Healthy individuals PFC activity is not severely affected by their mental state and cognitive activation successfully activates the PFC, supporting the hypothesis that EI is correlated with frontal cortical activation during the VFT in a nonclinical population. EI may play a vital role in reducing stress associated with depression and anxiety in our social lives. Although we failed to show a statistical correlation between TEIQue-SF and [Oxy-Hb] due to a sample size shortage, our preliminary study was the first to attempt to show the PFC activity of EI through a hemodynamic response. Future research may elucidate the role of EI in reducing psychological stress in social life.

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“…The VFT is a widely used neuropsychological scale mainly to measure cognitive, verbal, and executive functions ( Vaucheret Paz et al, 2020 ). It consists of three subtests to detect semantic, speech, and motion fluency, respectively.…”

Section: Methodsmentioning

confidence: 99%

Altered brain spontaneous activity in patients with cerebral small vessel disease using the amplitude of low-frequency fluctuation of different frequency bands

Chen,

Huang,

Zhang

et al. 2023

Front. Neurosci.

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BackgroundPrevious studies showed that cerebral small vessel disease (cSVD) is a leading cause of cognitive decline in elderly people and the development of Alzheimer’s disease. Although brain structural changes of cSVD have been documented well, it remains unclear about the properties of brain intrinsic spontaneous activity in patients with cSVD.MethodsWe collected resting-state fMRI (rs-fMRI) and T1-weighted 3D high-resolution brain structural images from 41 cSVD patients and 32 healthy controls (HC). By estimating the amplitude of low-frequency fluctuation (ALFF) under three different frequency bands (typical band: 0.01–0.1 Hz; slow-4: 0.027–0.073 Hz; and slow-5: 0.01–0.027 Hz) in the whole-brain, we analyzed band-specific ALFF differences between the cSVD patients and controls.ResultsThe cSVD patients showed uniformly lower ALFF than the healthy controls in the typical and slow-4 bands (pFWE < 0.05). In the typical band, cSVD patients showed lower ALFF involving voxels of the fusiform, hippocampus, inferior occipital cortex, middle occipital cortex, insula, inferior frontal cortex, rolandic operculum, and cerebellum compared with the controls. In the slow-4 band, cSVD patients showed lower ALFF involving voxels of the cerebellum, hippocampus, occipital, and fusiform compared with the controls. However, there is no significant between-group difference of ALFF in the slow-5 band. Moreover, we found significant “group × frequency” interactions in the left precuneus.ConclusionOur results suggested that brain intrinsic spontaneous activity of cSVD patients was abnormal and showed a frequency-specific characteristic. The ALFF in the slow-4 band may be more sensitive to detecting a malfunction in cSVD patients.

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Verbal Fluency Test in Children with Neurodevelopmental Disorders

Cited by 10 publications

References 22 publications

Abnormal Static and Dynamic Functional Network Connectivity in Patients With Presbycusis

Abnormal Static and Dynamic Functional Network Connectivity in Patients With Presbycusis

Correlation between trait emotional intelligence and prefrontal activation during a verbal fluency task: A functional near-infrared spectroscopy study

Altered brain spontaneous activity in patients with cerebral small vessel disease using the amplitude of low-frequency fluctuation of different frequency bands

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