Vergleichende Untersuchungen �ber den anaphylaktischen Schock und den Anaphylatoxinschock am intakten Meerschweinchen

A Simplified Method for the Extraction and Isolation of Histamine from Whole Blood, Plasma and Tissues for Fluorometric Histamine Analysis

“…Data in the literature for this value differ widely -compare for example the paper of Giertz and Hahn [1966], Our values agree very well with value of 0.37 pg/ml determined biologically by Giertz et al [1961], Anton and Sayre [1969] reported later a very much lower value of 0.08 pg/ml. This value appears, however, to be only relatively useful in view of the very low number of samples and the calculation of deviation.…”

“…Our plasma histamine values of 0.065 pg/ml again shows good agreement with the biologically determined value of Giertz et al [ 1961 ] of 0.064 pg/ml and those of Beall [1966] of 0.073 pg/ml. Values of 0.1 pg/ml have also been published by our group [Friedberg and Poppe.…”

Untersuchungen über die Beziehungen zwischen der Intensität der anaphylaktischen Reaktionen des Meerschweinchens und dem Zeitintervall zwischen Erst- und Re-Injektion des Antigens

“…In lungs perfused with Tyrode solution containing mephy ramine (10 yttg/ml), the intensity of bronchoconstriction was lower on the 10th day after sensitizing, but increased on the 20th and 40th day. 6. The time interval between the sensitizing and the challeng ing injection of the antigen is of importance with regard to the type of anaphylactic reaction in the guinea-pig.…”

Über den Entstehungsmechanismus des Spättodes im anaphylaktischen Schock beim Meerschweinchen

“…Hypothese, wonach die Spätletalität im anaphylaktischen Schock bei Meerschweinchen durch histaminunabhängige Mechanismen zustandekommt (14,16,18). Nachdem das Antihistaminicum nie mals die von Histamin hervorgerufene Frühletalität in Spätletalität umändert, können wir den anaphylaktischen Spättod nicht lang sameren Histaminwirkungen, die schwerer von Antihistaminicis verhindert werden, wie z.…”