Verhalten der essentiellen freien Aminos�uren im menschlichen Schwei�

Hungerland, H; Liappis, N

doi:10.1007/bf01488071

Cited by 6 publications

(2 citation statements)

References 13 publications

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“…Therefore, TA should be produced if sufficient AAAs are present on the skin. This is indeed the case as human sweat contains a comparatively high content (in the range of 300 μM or about 60 μg/ml) of AAAs [47][48][49][50][51] . In this context, approximately 10 μg/100 cm 2 of AAA and 5 μg/100 cm 2 of TA can be detected on our skin (Supplementary Table 1).…”

Section: Discussionmentioning

confidence: 79%

Trace amines produced by skin bacteria accelerate wound healing in mice

Luqman

Muttaqin²,

Yulaipi

et al. 2020

Commun Biol

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Certain skin bacteria are able to convert aromatic amino acids (AAA) into trace amines (TA) that act as neuromodulators. Since the human skin and sweat contain a comparatively high content of AAA one can expect that such bacteria are able to produce TA on our skin. Here we show that TA-producing Staphylococcus epidermidis strains expressing SadA are predominant on human skin and that TA accelerate wound healing. In wounded skin, keratinocytes produce epinephrine (EPI) that leads to cell motility inhibition by β2-adrenergic receptor (β2-AR) activation thus delay wound healing. As β2-AR antagonists, TA and dopamine (DOP) abrogate the effect of EPI thus accelerating wound healing both in vitro and in a mouse model. In the mouse model, the S. epidermidis wild type strain accelerates wound healing compared to its ΔsadA mutant. Our study demonstrates that TA-producing S. epidermidis strains present on our skin might be beneficial for wound healing.

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Section: Discussionmentioning

confidence: 79%

Trace amines produced by skin bacteria accelerate wound healing in mice

Luqman

Muttaqin²,

Yulaipi

et al. 2020

Commun Biol

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“…the ammonia content. For fresh sweat Morimoto and Johnson (1967) gave the concentration of ammonia as 3.1 mM and of urea 10.4 mM; the amino-acids serine, alanine and glycine were all found to be present in concentrations exceeding 0.4 mM though other authors differ on the relative abundances of the 21 amino-acids identified in sweat (Hungerland and Liappis 1972). Other nitrogen compounds occurring in smaller concentrations are uric acid, creatinine, creatine and choline.…”

Section: Discussionmentioning

confidence: 96%

The deposition of fingerprint films

Scruton

Robins

Blott

1975

J. Phys. D: Appl. Phys.

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The contact of human fingers with solid surfaces and their subsequent separation have been studied microscopically. Scanning electron microscopy and contact angle measurements have been applied to examine the deposit film. When a finger touches a surface, a film of liquid present on the finger spreads to produce apparent contact over much of the fingerprint ridge area. Lifting of the finger causes the film to recede and leave a deposit which may be either a distribution of droplets on a thin contaminating layer of adsorbed molecules, or a continuous film: which type is dependent on both the composition of the fingerprint and the nature of the substrate.

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The Sweat Glands

Natelson

1975

Principles of Applied Clinical Chemistry Chemical Background and Medical Applications

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Verhalten der essentiellen freien Aminos�uren im menschlichen Schwei�

Cited by 6 publications

References 13 publications

Trace amines produced by skin bacteria accelerate wound healing in mice

Trace amines produced by skin bacteria accelerate wound healing in mice

The deposition of fingerprint films

The Sweat Glands

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