“…In fact, studies have consistently shown that the main limiting factor for plant growth in the affected region is the low fertility of the Fundão dam tailings (Andrade et al, 2018;Coelho et al, 2020;Cruz, Gomes, Bicalho, Della Torre, & Garcia, 2020;Esteves et al, 2020). However, high concentrations of metals were also found in plants grown in tailings (Coelho et al, 2020;Esteves et al, 2020;Cruz, Gomes, Bicalho, & Garcia, 2021). When present at high concentrations in the soil, some metals can become toxic and affect important metabolic processes (e.g., inhibition of enzymatic activity, initiation of chlorosis, and lowering plant development/yield capacity) (Påhlsson, 1989;Nagajyoti, Lee, & Sreekanth, 2010;Onakpa, Njan, & Kalu, 2018).…”