Verrucous Carcinoma of the Ear

Proops, David W.; Hawke, W. M.; Harwood, Andrew R.; Nostrand, A. W. P. Van; Lunan, M.

doi:10.1177/000348948409300420

Cited by 20 publications

(7 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although more current reports do not indicate that adjuvant radiation incurs increased risk of dedifferentiation, there are very few reports that describe treated cases of verrucous carcinoma of the temporal bone [3,[16][17][18][19][20][21][22][23][24]. We present the 15th patient with this disease described in the English literature.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of submucous fibrosis and leukoplakia are associated with poor outcomes [15]. Verrucous carcinoma extremely rarely involves the temporal bone, and only 14 cases have been reported in literature [3,[16][17][18][19][20][21][22][23][24]. Because so few cases of verrucous carcinoma involving the middle ear and temporal bone have been described, there is no consensus on the best course of treatment for these lesions.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Temporal Bone Verrucous Carcinoma: Outcomes and Treatment Controversy

Miller¹,

Martin

Juillard³

et al. 2010

The Laryngoscope

View full text Add to dashboard Cite

Verrucous carcinoma is a rare tumor that presents in the head and neck with the most common sites being the oral cavity and larynx. Fourteen cases of verrucous carcinoma of the temporal bone have been described in literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. The study design included a literature review along with individual case report in the setting of a tertiary care medical center. Outcome analysis of all cases of verrucous carcinoma of the temporal bone, which are documented in the English literature, and presentation of a single patient report including gross, histologic and radiologic analyses were performed. The longest recorded survival for verrucous carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage of disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in verrucous carcinoma of the temporal bone remains controversial.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Temporal Bone Verrucous Carcinoma: Outcomes and Treatment Controversy

Miller¹,

Martin

Juillard³

et al. 2010

The Laryngoscope

View full text Add to dashboard Cite

show abstract

“…1 Verrucous carcinoma has been reported in almost all anatomic sites in the head and neck, including uncommon sites such as the orbit, 2 middle ear, [3][4][5] and temporal bone. 6 The incidence varies from 4.5% to 9%, and elderly men are most often afflicted.…”

mentioning

confidence: 99%

Verrucous carcinoma of the paranasal sinuses: Case report and clinical update

et al. 2003

View full text Add to dashboard Cite

show abstract

“…After the treatment of the antimicrotubule drug vinblastine, the patient got a better prognosis. In Proops et al’s report,14 5-fluorouracil and mitomycin C were used to treat the patient. Although no recent reports of recurrence (18 months), this case lacks longer follow-up data.…”

Section: Discussionmentioning

confidence: 99%

An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma

Tan¹,

Liu²,

Zhu³

et al. 2014

OTT

View full text Add to dashboard Cite

ObjectiveTo investigate the pathology and pathogenesis of and treatment methods for temporal bone verrucous carcinoma.Materials and methodsA single-patient report of verrucous carcinoma on the left external auditory canal is presented and analyzed along with all cases of temporal bone verrucous carcinoma that have been documented in the English literature.ResultsMost of the patients with verrucous carcinoma of the temporal bone have histories of surgery, trauma, or infection, and verrucous carcinomas are sensitive to antimicrotubule chemotherapeutic medicines. Adjuvant radiation therapy is not effective, but surgical treatment might be relatively more effective.ConclusionTemporal bone verrucous carcinoma has a poor prognosis; therefore, the preferred treatment is surgical resection facilitated with antimicrotubule chemotherapeutic treatment. Adjuvant radiation therapy is not a preferred treatment for temporal bone verrucous carcinoma.

show abstract

Verrucous Carcinoma of the Ear

Cited by 20 publications

References 20 publications

Temporal Bone Verrucous Carcinoma: Outcomes and Treatment Controversy

Temporal Bone Verrucous Carcinoma: Outcomes and Treatment Controversy

Verrucous carcinoma of the paranasal sinuses: Case report and clinical update

An individual drug-therapy and genetic testing report of temporal bone verrucous carcinoma

Contact Info

Product

Resources

About