Verrucous presentation of a granular cell tumour in scar tissue

Abstract

cobblestone-patterned plaque, and the histology was similar to that of fibroelastolytic papulosis.The pathogenesis of fibroelastolytic papulosis is unknown. Ultraviolet radiation from sun exposure may be less likely in the light of some rashes in sun-protected areas. Intrinsic ageing does not seem to be the only cause, because some cases have been reported in patients as young as 28 years. 3 Genetic and hormonal factors have also been considered because of a few familial cases reported as well as the predilection for women. 4 Autoimmune disease may be of less relevance to fibroelastolytic papulosis as previously reported. Recently, Song et al. 3 suggested that mild folliculitis or adnexal inflammation might be related to the pathogenesis of fibroelastolytic papulosis. Our patient exhibited the interface inflammation, which also indicated the pathogenesis was likely to be due to inflammatory process.We recommend that serial biopsies of future cases be performed to look for an acute inflammatory phase that preceeds the chronic more commonly reported histopathology.

Granular cell tumor on a cesarean section scar

“…A variety of lesions can occur at the surgical scar site, including traumatic neuromas, sarcomas, and desmoid tumors, 2 and the case presented here adds GCT to this list. Given the fact that these lesions may not be differentiated clinically, histopathology and immunohistochemistry are necessary to establish the diagnosis.…”

“…So far, only rare cases of GCT have been reported developing at skin trauma sites, either the site of vaccination or surgical incision. 2 , 3 , 4 , 5 , 6 Murcia et al 5 published the first case of GCT occurring on the vulvar episiotomy scar presenting as a subcutaneous nodule found during a routine gynecologic examination. In another case reported by Sułkowski et al, 6 GCT was found on a cesarean section scar at the fascia level, mimicking an endometrial tumor.…”

“…In another case reported by Sułkowski et al, 6 GCT was found on a cesarean section scar at the fascia level, mimicking an endometrial tumor. Recently, Chasseuil et al 2 reported a verrucous GCT with a deep tissue component in a laparotomy scar. In contrast, in our patient, the tumor presented as a cutaneous lesion and did not extend beyond the dermis.…”

“… 1 Other affected areas include breast, gastrointestinal or respiratory tract, thyroid gland, bladder, central nervous system, female genitalia, 1 and the site of skin trauma. 2 , 3 , 4 , 5 , 6 GCT has a female preponderance and usually occurs between the third and fifth decades of life. 1 In this case report, we describe a GCT arising in a cesarean section scar.…”

Atypical granular cell tumor developing within a tattoo

“…There have been several other reports of GCTs developing in sites of previous localized trauma, including 2 cases of GCTs developing at vaccination sites and several cases of GCTs occurring at previous surgical sites. [6][7][8][9] In these cases, the temporal relationship between the traumatic insult and the development of the GCT varied between 2 weeks and greater than 8 years. Although none of the previous reported cases developed as far removed temporally from the initial dermal trauma as in our patient, it is possible that the chronic scar tissue or inflammation caused by the tattoo placement predisposed the patient to development of a GCT.…”