Versatile coordination chemistry of rhodium complexes containing the bis(trimethylsilylmethyl)tellane ligand

Vigo, Ludmila; Poropudas, Merja J.; Salin, Pekka; Oilunkaniemi, Raija; Laitinen, Risto S.

doi:10.1016/j.jorganchem.2009.02.001

Cited by 9 publications

(5 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A1 was synthesized according to literature methods, , and A2 was prepared by a procedure similar to that reported for A3 using indazole instead of imidazole. Rh(III) complexes used for fitting the XAS data were synthesized according to literature procedures ( S1 , S2 , S3 , S4 , , S5 , M1 , M2 , M3 , M4 , M5 , M6 , M7 , M8 , M9 , O1 , O2 ) or purchased from the commercial suppliers ( S6 , O3 ). Structures of these Rh(III) model complexes are presented in Chart , and their structural formulas, types of donor atoms, and published synthetic procedures are summarized in Table S2 in the Supporting Information.…”

Section: Methodsmentioning

confidence: 99%

Reactivity and Transformation of Antimetastatic and Cytotoxic Rhodium(III)–Dimethyl Sulfoxide Complexes in Biological Fluids: An XAS Speciation Study

et al. 2019

View full text Add to dashboard Cite

Rhodium(III) anticancer drugs can exert preferential antimetastatic or cytotoxic activities, which are dependent on subtle structural changes. In order to delineate factors affecting the biotransformations and speciation, mer,cis-[RhCl3(S-dmso)2(O-dmso)] (A1) and mer,cis-[RhCl3(S-dmso)2(2N-indazole)] (A2) have been studied by X-ray absorption spectroscopy (XAS). Interactions of these complexes with saline buffer, cell culture media, serum proteins (albumin and apo-transferrin), native and chemically degraded collagen gels, and A549 cells have been studied using linear combination fitting (LCF) and 3D scatter plots of XAS data. Following initial aquation and hydrolysis reactions involving stepwise displacement of Cl– and S-/O-dmso ligands, the Rh(III) complexes underwent further ligand substitution reactions with biological nucleophiles (e.g., amino acid residues of serum proteins). The reaction of A1 with chemically degraded collagen gel was postulated to be a key reason for its antimetastatic activity. Analyses of the XAS of Rh-treated bulk cells were consistent with structure–reactivity relationships in which the more reactive A1 was predominantly antimetastatic and the less reactive A2 was predominantly cytotoxic, showing relationships parallel to typical Ru(III) anticancer agents, i.e., NAMI-A ([ImH] trans-[RuCl4(S-dmso)(N-imidazole)2], ImH = imidazolium cation) and KP1019/NKP1339 (KP1019, [IndH] trans-[RuCl4(N-indazole)2], IndH = indazolium cation; NKP1339, sodium trans-[RuCl4(2N-indazole)2]), respectively.

show abstract

Section: Methodsmentioning

confidence: 99%

Reactivity and Transformation of Antimetastatic and Cytotoxic Rhodium(III)–Dimethyl Sulfoxide Complexes in Biological Fluids: An XAS Speciation Study

et al. 2019

View full text Add to dashboard Cite

show abstract

“…12 As a consequence of the above-mentioned variety of interactions, the complexes of both metals are often involved in supramolecular frameworks, which are currently of increasing interest. 13 In this work we have explored the effect of the identity of organic substituent on the solid-state stereochemistry of a number of telluroether complexes of Ag(I) and Cu(I) as a part of a systematic study of complexes involving late transition metals such as Pt and Pd, 14 Ru, 15 Rh, 16 and Hg, 17 and organochalcogen ligands. Some related diphenylselane complexes have been included in this study for comparison.…”

Section: Introductionmentioning

confidence: 99%

Versatile solid-state coordination chemistry of telluroether complexes of silver(i) and copper(i)

Poropudas¹,

Vigo²,

Oilunkaniemi³

et al. 2013

Dalton Trans.

Self Cite

View full text Add to dashboard Cite

The treatment of EPh2 (E = Te, Se) with Ag(O3SCF3) or Cu(O3SCF3)·1/2C6H6 in dichloromethane yields isomorphous complexes [Ag(TePh2)3](O3SCF3) (1), [Cu(TePh2)3](O3SCF3) (2), and [Cu(SePh2)3](O3SCF3) (3). The related reaction of TeTh2 (Th = 2-thienyl, C4H3S) with Cu(O3SCF3)·1/2C6H6 affords [Cu(TeTh2)3](O3SCF3) (4). While not isomorphic with 1-3, its crystal structure bears a close relationship with them. The reaction of TeTh2 or SePh2 with Ag(O3SCF3) yields [Ag(TeTh2)2](O3SCF3) (5) and [Ag(SePh2)2](O3SCF3) (6), respectively. They form dinuclear complexes, the silver centers of which are coordinated to two terminal R2E ligands and linked together by two bridging CF3SO3(-) ligands. The dinuclear complexes further form supramolecular networks through π-π stacks of the aromatic rings. The treatment of Ag(O3SCF3) with Te(CH2SiMe3)2 results in the formation of a mixture containing polynuclear [Ag{Ag[Te(CH2SiMe3)2]}4]n(O3SCF3)5n (7) and [Ag{Te(CH2SiMe3)2}]n(O3SCF3)n (8). The cyclic repeating units in 7 are connected to polymeric chains by two bridging CF3SO3(-) ligands. 8 contains a [-Ag-Te(CH2SiMe3)2-]n polymer. There are only weak van der Waals interactions between the polymer chains of 7 and 8.

show abstract

“…2). 70 Most of these complexes have shown issues with their solubility in common organic solvents. The solubility issues have been overcome with the development of a new class of telluroether in which the backbone consists of a morpholine group.…”

Section: Rhodium and Iridiummentioning

confidence: 99%

Emerging trends in organotellurolate chemistry derived from platinoids

Chauhan

Shivran

2017

RSC Adv.

View full text Add to dashboard Cite

show abstract

Versatile coordination chemistry of rhodium complexes containing the bis(trimethylsilylmethyl)tellane ligand

Cited by 9 publications

References 26 publications

Reactivity and Transformation of Antimetastatic and Cytotoxic Rhodium(III)–Dimethyl Sulfoxide Complexes in Biological Fluids: An XAS Speciation Study

Reactivity and Transformation of Antimetastatic and Cytotoxic Rhodium(III)–Dimethyl Sulfoxide Complexes in Biological Fluids: An XAS Speciation Study

Versatile solid-state coordination chemistry of telluroether complexes of silver(i) and copper(i)

Emerging trends in organotellurolate chemistry derived from platinoids

Contact Info

Product

Resources

About