We adopt thick-film technology to produce ultra high vacuum compatible interfaces for electrical signals. These interfaces permit voltages of hundreds of volts and currents of several amperes and allow for very compact vacuum setups, useful in quantum optics in general, and in particular for quantum information science using miniaturized traps for ions (Kielpinski et al. in Nature 417:709, 2002) or neutral atoms (Folman et al. circuits can also be useful as pure in-vacuum devices. We demonstrate a specific interface which provides 11 current feedthroughs, more than 70 dc feedthroughs and a feedthrough for radio frequencies. We achieve a pressure in the low 10 −11 mbar range and demonstrate the full functionality of the interface by trapping chains of cold ytterbium ions, which requires the presence of all of the above mentioned signals. In order to supply precise time-dependent voltages to the ion trap, a versatile multi-channel device has been developed.