1899
DOI: 10.1007/bf02792160
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Versuche über Cocainisirung des Rückenmarkes

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Cited by 342 publications
(86 citation statements)
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“…August Bier was the first to inject cocaine into the spinal space in 1898. 42 Cocaine congeners such as norcocaine, pseudococaine, and tropacocaine, and isomers of phenyltropane analogs were later brought into practice from 1902.…”
Section: Historymentioning
confidence: 99%
“…August Bier was the first to inject cocaine into the spinal space in 1898. 42 Cocaine congeners such as norcocaine, pseudococaine, and tropacocaine, and isomers of phenyltropane analogs were later brought into practice from 1902.…”
Section: Historymentioning
confidence: 99%
“…Dr Bier surmised that the headache was attributed to loss of CSF. 3 Reduction in needle size and development in its design have led to a significant reduction in the incidence of PDPH.…”
Section: Historymentioning
confidence: 99%
“…In the past ten years alone, more than two publications have appeared every single day on the subject, equally distributed between analgesic effects in major surgery, obstetric anaesthesia, side effects and technical aspects . Apart from subarachnoidal analgesia, which was first introduced in 1898 (Bier 1899), it is hard to imagine a method of analgesia having been similarly subjected to scientific study. In the case of spinal anaesthesia, the foundation for its use is still overwhelming by its significant reduction in perioperative morbidity and mortality compared to general anaesthesia (Rodgers 2000).…”
Section: The Epidural Catheter In a Historical Perspectivementioning
confidence: 99%